1093 incidence of infection in relation to duration of rupture of membranes (rom) in premature infants

ABSTRACT From July 1976 to Dec. 1979, 300 premature infants, weighing between 1000 and 2300 gm were studied for the incidence of infection in relation to duration of ROM. They were divided

into 6 groups of infants with 0-15/60, 16/60-23, 24-71 and greater than 72 hours of ROM. There were 82, 127, 51 and 40 infants in each group respectively. The incidence of proven infection

was 8% (24) out of which 5% (15) had positive blood culture, 3% (4) had meningitis and 3.3% (10) had urinary tract infection. The incidence of clinical sepsis was 33.3% (100). The incidence

of clinical and proven sepsis was not related to the duration of ROM. The incidence of antibiotic therapy was significantly related to the duration of ROM particularly in infants more than

32 weeks and 1500 gm. When they were small and extremely immature, 2/3 of them were on antibiotic therapy and it was not related to the duration of ROM. As the duration of ROM increases, the

incidence of amnionitis and maternal antibiotic therapy increased only when the infants were greater than 32 weeks and 1500 gm. There were no correlations between the duration of ROM and

the incidence of meconium stained amniotic fluid, fetal distress and severe perinatal asphyxia. Infants 32 weeks or less with greater than 72 hours of ROM had the lowest incidence of severe

perinatal asphyxia. The mortality rate was not related to the duration of ROM. However, when there was no associated proven infection, significantly higher mortality was noted in infants

with greater than 24 hrs. of ROM which was often associated with severe perinatal asphyxia. This study revealed that the duration of ROM did not seem to effect the incidence of infection,

fetal distress, perinatal asphyxia and mortality in premature infants. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Albert Einstein Coll. of Med., Bronx-Lebanon Hosp. Ctr.,

Dept. of Ped. and Obst., Bronx, NY. J J Yoon, A E Esquea, J N Rao, M N Wijesinghe & M Cohen Authors * J J Yoon View author publications You can also search for this author inPubMed 

Google Scholar * A E Esquea View author publications You can also search for this author inPubMed Google Scholar * J N Rao View author publications You can also search for this author

inPubMed Google Scholar * M N Wijesinghe View author publications You can also search for this author inPubMed Google Scholar * M Cohen View author publications You can also search for this

author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Yoon, J., Esquea, A., Rao, J. _et al._ 1093 INCIDENCE OF INFECTION IN

RELATION TO DURATION OF RUPTURE OF MEMBRANES (ROM) IN PREMATURE INFANTS. _Pediatr Res_ 15 (Suppl 4), 625 (1981). https://doi.org/10.1203/00006450-198104001-01119 Download citation * Issue

Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-01119 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link

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