The cyclooxygenase-2 stucture: new drugs for an old target?

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The cyclooxygenase-2 stucture: new drugs for an old target?"


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The crystal structure of human cyclooxygenase-2 offers a unique opportunity for the design of new nonsteroidal anti-inflammatory drugs and may also provide insights into the mechanisms of


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in _Peroxidases in Chemistry and Biology_ (eds J. Everse, K.E. Everse & M.B. Grisham) 293–334 (CRC Press, BocaRaton, 1991). Google Scholar  Download references AUTHOR INFORMATION AUTHORS


AND AFFILIATIONS * Department of Biochemistry, Michigan State University, East Lansing, Michigan, 48824-1319, USA R. Michael Garavito Authors * R. Michael Garavito View author publications


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new drugs for an old target?. _Nat Struct Mol Biol_ 3, 897–901 (1996). https://doi.org/10.1038/nsb1196-897 Download citation * Issue Date: 01 November 1996 * DOI:


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