Succeeding where others have failed

Access through your institution Buy or subscribe Jade Williamson tells of spending her childhood wrapped head-to-toe in bandages, with daily trips to the hospital. Eczema sufferers like Jade

therefore welcomed the news that the gene that underlies their condition, and also predisposes to asthma, has been identified. The gene encodes filaggrin, which normally keeps foreign

bodies out of the skin (_Glasgow Evening Times_, 20 March 2006). Mutation of one gene copy leads to flaky, dry skin, with deletion of both copies leading to severe eczema. The news, which

was published in _Nature Genetics_, was hailed as a "real step forward" by the National Eczema Society, which added: "Above all, it answers the age-old question asked by most

eczema sufferers — 'why?'"(_The Scotsman_, 20 March 2006). This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your

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our FAQs * Contact customer support Authors * Tanita Casci View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and

permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Casci, T. Succeeding where others have failed. _Nat Rev Genet_ 7, 336 (2006). https://doi.org/10.1038/nrg1863 Download citation * Issue Date:

01 May 2006 * DOI: https://doi.org/10.1038/nrg1863 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link

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