Pparγ and colorectal carcinoma: conflicts in a nuclear family
Pparγ and colorectal carcinoma: conflicts in a nuclear family"
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ABSTRACT Two new mouse studies suggest that PPARγ agonists may promote tumorigenesis in colon epithelium whereas a third study in humans indicates a possible protective role for these drugs
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Contact customer support REFERENCES * Lehmann, J.M. _ et al._ An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). _
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on polyp phenotype in multiple intestinal neoplasia mice. _Proc. Natl. Acad. Sci. USA_ 94, 3308–3313 (1997). Article CAS Google Scholar Download references ACKNOWLEDGEMENTS _I thank R.
Xavier and J. Avruch for helpful comments and B. Spiegelman for the communication of unpublished results._ AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Molecular Biology,
Massachusetts General Hospital, Boston, 02114, Massachusetts, USA Brian Seed Authors * Brian Seed View author publications You can also search for this author inPubMed Google Scholar RIGHTS
AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Seed, B. PPARγ and colorectal carcinoma: Conflicts in a nuclear family. _Nat Med_ 4, 1004–1005 (1998).
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