Csp #2001 va intrepid | veterans affairs
Csp #2001 va intrepid | veterans affairs"
- Select a language for the TTS:
- UK English Female
- UK English Male
- US English Female
- US English Male
- Australian Female
- Australian Male
- Language selected: (auto detect) - EN
Play all audios:
This is a prospective, randomized, double-blind, placebo-controlled, investigation of a six week course of adjunctive rifampin vs. adjunctive matched placebo (riboflavin) added to backbone
antibacterial therapy for the treatment of diabetic foot osteomyelitis. Backbone antibacterial therapy will be with single or multiple agents selected by the clinical treatment team based
either on culture results or standard empiric therapy, and which can be administered either intravenously or orally. Rifampin will be dosed at 600 mg daily. The primary outcome measure is
amputation-free survival. Amputation events include both below- and above-ankle amputations. Primary outcomes will be determined by systematic medical record review and through confirmatory
research visits, phone calls and, as needed, information from non-VA providers. The results for amputation-free survival will be analyzed by means of a two-sided log-rank test. The secondary
outcomes of complete wound epithelialization and remission of osteomyelitis will be determined by direct examination by the site investigators. The study will initially enroll and randomize
a total of 880 study participants to receive either rifampin or placebo (riboflavin) in addition to backbone antibiotic therapy prescribed by their clinician. Investigators expect to
enroll, on average, close to one subject per month per site (10-12 per year/site) at 28 VA medical centers to achieve total randomization of 880 subjects over three years. In meeting this
average site enrollment projection, Investigators anticipate variation in enrollment between larger and smaller sites, and between high-performing and low-performing sites. Subjects will be
followed through the end of the second year after randomization or until a study primary endpoint event (amputation or death) occurs. On average, study participants will be followed for 1.8
years through systematic review of medical records, and by study visits and phone calls.
Trending News
Colonel, cop son & fraudster nabbed at midnight party in ahmedabadCops yet to ascertain if the girls were drunk too. Guess who is the biggest catch for the police in the booze party bust...
Pardon Our InterruptionPardon Our Interruption As you were browsing something about your browser made us think you were a bot. There are a few ...
The s-component fold: a link between bacterial transporters and receptorsABSTRACT The processes of nutrient uptake and signal sensing are crucial for microbial survival and adaptation. Membrane...
Sa20 auction 2022: complete list of sold and unsold players at sa20 players auctionThe player auction for the inaugural season of South Africa’s upcoming new T20 League, the SA20 was held in Capetown on ...
He Had the Beef All Along - Los Angeles TimesYes, his hamburgers are fresh and square like his public persona. Yes, the orphaned onetime busboy was a modern Horatio ...
Latests News
Csp #2001 va intrepid | veterans affairsThis is a prospective, randomized, double-blind, placebo-controlled, investigation of a six week course of adjunctive ri...
Hot cannes package: chris hemsworth, tiffany haddish team for buddy action comedy ‘down under cover’EXCLUSIVE: In what will quickly become one of the hot film packages on the Croisette, Deadline hears that _Avengers: End...
Part of brittany put on drought alert, residents asked to save waterIT COMES AFTER A SIGNIFICANT LACK OF RAINFALL OVER THE SUMMER The department of Morbihan in Brittany has this week been ...
Page Not Found很抱歉,你所访问的页面已不存在了。 如有疑问,请电邮[email protected] 你仍然可选择浏览首页或以下栏目内容 : 新闻 生活 娱乐 财经 体育 视频 播客 新报业媒体有限公司版权所有(公司登记号:202120748H)...
Life sciences firm closing 2 maryland facilities, laying off workersInternational life sciences firm Catalent is shutting down two large Maryland facilities and laying off workers, public ...