Starvation induces metabolic hepatocyte reprogramming

The liver performs gluconeogenesis, the de novo production of glucose during extended fasting and starvation. A study by Okada et al. now highlights spatiotemporal metabolic reprogramming in

hepatocytes during metabolic transitions between feeding states. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution

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references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Novartis Biomedical Research, Novartis Pharma AG, Basel, Switzerland Coenraad F. Slabber & Jan S. Tchorz Authors * Coenraad F.

Slabber View author publications You can also search for this author inPubMed Google Scholar * Jan S. Tchorz View author publications You can also search for this author inPubMed Google

Scholar CORRESPONDING AUTHOR Correspondence to Jan S. Tchorz. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing interests. RIGHTS AND PERMISSIONS Reprints and

permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Slabber, C.F., Tchorz, J.S. Starvation induces metabolic hepatocyte reprogramming. _Nat Metab_ 7, 864–866 (2025).

https://doi.org/10.1038/s42255-025-01286-x Download citation * Published: 25 April 2025 * Issue Date: May 2025 * DOI: https://doi.org/10.1038/s42255-025-01286-x SHARE THIS ARTICLE Anyone you

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