Effects of microbiome transplants on fly microbiome

Access through your institution Buy or subscribe The gut microbiome greatly influences the host organism. However, it is still unknown how microbial diversity affects systemic functions and

how the microbiome content and functions change across the host lifespan. A study in _Scientific Reports_ studying _Drosophila_ shows that transplanting microbiomes from flies of different

ages affects the host in an unexpected and complex manner. When the researchers fed the flies with a suspension enriched with microbiome from either young or old flies or a control feed for

weeks, microbial diversity increased in all groups as the flies aged. When analyzing the composition of the enriched microbiomes, the team observed different bacterial populations when

comparing animals enriched with young or old microbiomes, with both showing differences from control animals. This observation suggests that microbial enrichment alone is sufficient to alter

the microbiome of flies. Additionally, when studying fly longevity and locomotion, supplemented groups lived 10% longer, but there was no effect on activity when comparing the three groups.

These results show that in flies, microbiome transplants can alter the host microbiome, but it is not enough to change their phenotype. ORIGINAL REFERENCE: Wesseltoft, J.B. et al. _Sci.

Rep_. 14, 7799 (2024) This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution ADDITIONAL ACCESS OPTIONS: * Log in * Learn about

institutional subscriptions * Read our FAQs * Contact customer support AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Lab Animal http://www.nature.com/laban/ Jorge Ferreira Authors * Jorge

Ferreira View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Jorge Ferreira. RIGHTS AND PERMISSIONS Reprints and

permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Ferreira, J. Effects of microbiome transplants on fly microbiome. _Lab Anim_ 53, 109 (2024). https://doi.org/10.1038/s41684-024-01369-4

Download citation * Published: 03 May 2024 * Issue Date: May 2024 * DOI: https://doi.org/10.1038/s41684-024-01369-4 SHARE THIS ARTICLE Anyone you share the following link with will be able

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