Crispr target prediction remains blunt tool for clinical applications

Computational approaches to predict gene editing repair by CRISPR endonucleases remain a work in progress. Access through your institution Buy or subscribe This is a preview of subscription

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* Learn about institutional subscriptions * Read our FAQs * Contact customer support CHANGE HISTORY * _ 20 MARCH 2019 In the version of this article initially published, we reported that

Sangamo’s SB-318 had failed to change baseline leukocyte α-l-iduronidase in a phase 1/2 trial. The drug failed to change baseline plasma α-l-iduronidase but did increase leukocyte

α-l-iduronidase to within the normal range. The error has been corrected in the HTML and PDF versions of the article. _ AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Cambridge, UK John

Hodgson Authors * John Hodgson View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE

THIS ARTICLE Hodgson, J. CRISPR target prediction remains blunt tool for clinical applications. _Nat Biotechnol_ 37, 204–205 (2019). https://doi.org/10.1038/s41587-019-0057-7 Download

citation * Published: 04 March 2019 * Issue Date: March 2019 * DOI: https://doi.org/10.1038/s41587-019-0057-7 SHARE THIS ARTICLE Anyone you share the following link with will be able to read

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