Rethinking articular cartilage regeneration based on a 250-year-old statement

Cartilage has a limited healing capacity; however, studies into the basic biological characteristics, formation and structural maintenance of the cartilage collagen network are providing

explanations for the failure of current therapeutic approaches, urging us to rethink our approach to the regeneration of articular cartilage. Access through your institution Buy or subscribe

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ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Hunter, W. Of the structure and disease of the articulating

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Google Scholar  Download references ACKNOWLEDGEMENTS The authors acknowledge the Dutch Arthritis Foundation (LLP-12 (to J.M.) and LLP-22 (to P.R.v.W.)), and the Netherlands Organization for

Scientific Research (Materials Driven Regeneration, 024.003.013 (to J.M.)) for financial support. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Orthopaedics, University Medical

Centre Utrecht, Utrecht, Netherlands Jos Malda * Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands Jos Malda & P. René van Weeren *

Department of Functional Materials in Medicine and Dentistry and the Bavarian Polymer Institute, University of Würzburg, Würzburg, Germany Jürgen Groll Authors * Jos Malda View author

publications You can also search for this author inPubMed Google Scholar * Jürgen Groll View author publications You can also search for this author inPubMed Google Scholar * P. René van

Weeren View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Jos Malda. ETHICS DECLARATIONS COMPETING INTERESTS The

authors declare no competing interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Malda, J., Groll, J. & van Weeren, P.R. Rethinking articular

cartilage regeneration based on a 250-year-old statement. _Nat Rev Rheumatol_ 15, 571–572 (2019). https://doi.org/10.1038/s41584-019-0278-7 Download citation * Published: 31 July 2019 *

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