START smuggling CoQ to fight ferroptosis
START smuggling CoQ to fight ferroptosis"
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Extramitochondrial coenzyme Q (CoQ) can function as a potent anti-ferroptosis radical trapper. However, it is largely unknown how CoQ is transported from mitochondria to the plasma membrane.
A study now suggests that PARL-mediated STARD7 processing is responsible for the cellular distribution of CoQ.
D.L. is an inventor of a patent relevant to autophagy. X.J. is an inventor of patents relevant to cell death and autophagy. He is also a consultant and equity holder of Exarta Therapeutics
and Lime Therapeutics.
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