Prognostic significance of pre-treatment neutrophil-to-lymphocyte ratio (NLR) in patients with oropharyngeal cancer treated with radiotherapy

Nature

Prognostic significance of pre-treatment neutrophil-to-lymphocyte ratio (NLR) in patients with oropharyngeal cancer treated with radiotherapy"


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This study aimed to evaluate the prognostic value of pre-treatment NLR in patients with oropharyngeal cancer.


Patients who completed definitive radiotherapy (RT) for oropharyngeal cancer and had blood counts taken pre-RT from 2002 to 2013 were included. NLR was calculated as total


neutrophil/lymphocytes. Survival rates were estimated using the Kaplan–Meier method. Univariable and multivariable analyses were conducted with linear and Cox regression methods. NLR was


analysed posteriori and dichotomised on the discovered median.


Eight hundred and forty-eight patients were analysed. The median pre-RT NLR was 3. Patients with NLR of


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