No influence of maternal vitamin k supplementation on vitamin k concentration in breastmilk

ABSTRACT Haemorrhagic disease in breastfed infants caused by vitamin K deficiency can be prevented by oral or parenteral vitamin K administration. Low vitamin K intake with breastmilk may be

responsible for the late onset vitamin K deficiency. Therefore we measured vitamin K intake of 28 healthy term breastfed infants at 6, 28 and 90 days of age in a longitudinal randomized

study. 16 mothers received a daily oral vitamin K1 supplement (100ug, Milusan®). Milk intake was evaluated by 24 hour testweighing and vitamin K1 concentration in milk was measured employing

the HPLC-technique. Vitamin K, intake was similar in the two groups and no influence of age was detected. (Tab., intake in ug/d). However, vitamin K1 intake of all infants was substantially

below the RDI value of 10ug/day. (Am.J.Clin.Nutr;1987;45;687-92). Therefore low vitamin K intake with breastmilk might be responsible for late onset vitamin K deficiency in some infants.

ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Dept. Pediatrics, Univ. of Vienna, Austria B Pietschnig, F Haschke & E Schuster * Research Dept., Milupa, Friedrichsdorf, FRG V

Veitl & G Harzer * Dept. Haematology, Guy's Hospital, Univ. London, UK M J Shearer Authors * B Pietschnig View author publications You can also search for this author inPubMed 

Google Scholar * F Haschke View author publications You can also search for this author inPubMed Google Scholar * V Veitl View author publications You can also search for this author

inPubMed Google Scholar * G Harzer View author publications You can also search for this author inPubMed Google Scholar * M J Shearer View author publications You can also search for this

author inPubMed Google Scholar * E Schuster View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS

ARTICLE CITE THIS ARTICLE Pietschnig, B., Haschke, F., Veitl, V. _et al._ NO INFLUENCE OF MATERNAL VITAMIN K SUPPLEMENTATION ON VITAMIN K CONCENTRATION IN BREASTMILK. _Pediatr Res_ 26, 514

(1989). https://doi.org/10.1203/00006450-198911000-00090 Download citation * Issue Date: 01 November 1989 * DOI: https://doi.org/10.1203/00006450-198911000-00090 SHARE THIS ARTICLE Anyone

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