557 decreased bone mineral content (bmc) in breast-fed infants without supplemental vitamin d (d): “catch up” mineralization at 6 months and one year; possible. Effects on length

Nature

557 decreased bone mineral content (bmc) in breast-fed infants without supplemental vitamin d (d): “catch up” mineralization at 6 months and one year; possible. Effects on length"


Play all audios:

Loading...

ABSTRACT We previously reported a double blind randomized prospective study of 9 exclusively breast-fed infants without supplemental D (placebo, plac) and 9 exclusively breast-fed infants on


supplement of 400 IU D/d (suppl.); 12 infants were fed exclusively Similac 20 cal/oz (form). As reported, at 3 mos plac had significantly lower BMC (modified photon absorptiometry) and


serum 25-OH D. By 6 mos, serum 25-OHD had decreased and was still lower in plac vs suppl. (12.9±4.0 SE vs 32.7±4.1ng/ml. p<.01). BMC at 6 mos was 70±6, 75±5, and 94±7mg/cm for plac suppl.


and form; plac and suppl. did not differ; plac was less than form (p<.05). After 6 mos, the study was unblinded, infants received solids and breast-fed infants received 400 IU D/d. 10


form and 13 breast-fed infants were seen at 12 mos, when serum 25-OHD, parathyroid hormone, calcitonin, Ca, P, Mg and alkaline phosphatase did not differ between plac and suppl. BMC at 12


mos was 120±19, 108±20, and 132±8mg/cm for plac, suppl. and form and did not differ; grps did not differ in wt, but plac was shorter (73.3±.38cm) than suppl. (75.8± .89cm, p<.1) or form


(75.8±0.32cm, p<.02); one way analysis of variance for 3 grps, p<.05. Thus, vitamin D supplements may be necessary for optimal bone mineralization in breast-fed infants but “catchup”


mineralization may occur in infants not given D initially. We speculate that D supplements may also be necessary for optimal body length in breast-fed infants. ARTICLE PDF AUTHOR INFORMATION


AUTHORS AND AFFILIATIONS * U Cincinnati, F R Greer, J E Searcy, R S Levin, J J Steichen & R C Tsang Authors * F R Greer View author publications You can also search for this author


inPubMed Google Scholar * J E Searcy View author publications You can also search for this author inPubMed Google Scholar * R S Levin View author publications You can also search for this


author inPubMed Google Scholar * J J Steichen View author publications You can also search for this author inPubMed Google Scholar * R C Tsang View author publications You can also search


for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Greer, F., Searcy, J., Levin, R. _et al._ 557 DECREASED BONE


MINERAL CONTENT (BMC) IN BREAST-FED INFANTS WITHOUT SUPPLEMENTAL VITAMIN D (D): “CATCH UP” MINERALIZATION AT 6 MONTHS AND ONE YEAR; POSSIBLE.EFFECTS ON LENGTH. _Pediatr Res_ 15 (Suppl 4),


533 (1981). https://doi.org/10.1203/00006450-198104001-00570 Download citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-00570 SHARE THIS ARTICLE Anyone


you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the


Springer Nature SharedIt content-sharing initiative


Trending News

Salman rushdie's 'feisty and defiant' humour is intact, says son

New York: Salman Rushdie is still in a critical condition, but his usual feisty and defiant sense of humour remains inta...

Washington grown | organic produce preview | season 12 | episode 1207

- On the next episode of "Washington Grown" we're learning about organic produce. Val's visiting Lit...

Poll shows print newspaper readership on the decline - aarp bulletin

An era in which Americans read a daily newspaper with their morning coffee, or on the subway on their way to work, is fa...

Blackstone group invests up to $2 billion in alnylam, a big bet on the cambridge biotech

The private equity firm Blackstone Group is investing up to $2 billion in Alnylam Pharmaceuticals, a big bet on the Camb...

Family 'heartbroken' after 'harmless' man stabbed to death in 'race hate crime'

The family of a "kind-hearted" and "harmless" man who died after being attacked in a 'race-hate...

Latests News

557 decreased bone mineral content (bmc) in breast-fed infants without supplemental vitamin d (d): “catch up” mineralization at 6 months and one year;

ABSTRACT We previously reported a double blind randomized prospective study of 9 exclusively breast-fed infants without ...

How to draw er diagram using chatgpt

In this story, you’ll be learning all about entity relationship diagrams or ERDs. we are going to start by discussing a ...

Australian policy review backs huge cuts in research funding

Access through your institution Buy or subscribe sydney John Moore, Minister for Industry, Science and Tourism in the Co...

'first-class' yorkshire hotel to become 12 holiday homes under new plans

A 'first-class' Whitby hotel is set to be transformed into holiday homes - if plans are given the go-ahead. Lo...

Number of high-protein containing meals correlates with muscle mass in pre-frail and frail elderly

ABSTRACT BACKGROUND Aging is accompanied by the inability to optimally respond to anabolic stimulus of nutrition, with c...

Top