1121 ECHOCARDIOGRAPHIC EVIDENCE FOR IMPAIRED MYOCARDIAL PERFORMANCE IN CHILDREN WITH TYPE I DIABETES MELLITUS

Myocardial performance was assessed by M-mode echocardiography in 33 children (6 8/12-19 3/12 yr) with Type I diabetes mellitus and in 51 normal children (6 2/12-18 8/12). Left ventricular

end systolic dimension (LVESD), and left ventricular end systolic volume/M2 (LVESV/M2) were greater in diabetics than controls. Left ventricular ejection fraction (LVEF), minor axis

shortening (MAS), and velocity of circumferential fiber shortening (VCF) were less in diabetics than controls.

Hgb A1 levels in children with diabetes (15.5±0.6%, range 10.1-22.2%, normal 5.9-8.7%) correlated with clinical assessment of control (p