1027 CYTOMEGALOVIRUS (CMV) SEROLOGY IN SUDDEN INFANT DEATH SYNDROME (SIDS): LACK OF CORRELATION WITH CHLAMYDIA TRACHOMATIS SEROLOGY
1027 CYTOMEGALOVIRUS (CMV) SEROLOGY IN SUDDEN INFANT DEATH SYNDROME (SIDS): LACK OF CORRELATION WITH CHLAMYDIA TRACHOMATIS SEROLOGY"
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We found Chlamydia trachomatis (C.t.) seropositivity to be significantly more frequent in SIDS than living controls. Because infection with CMV has been proposed to act synergistically with
C.t. in producing infant respiratory infection and in utero viral infections have been postulated to play a role in SIDS, CMV complement fixing antibody titers were measured in serum from 29
SIDS, age 12.3±5.8wks, and 23 living hospitalized controls (C), age 13.5±6.7wks on which C.t. immunofluorescent antibody serologies had been performed. Cord blood (CB) from 19 black lower
socioeconomic infants was similarly studied. Although 34% of SIDS were CMV seropositive, suggesting previous or ongoing maternal CMV infection, this was not different from controls. Only 4
of 11 SIDS with high C.t. titers (≥1:1024) were CMV seropositive, all at low titers. Although CMV and C.t. titers were correlated (r= .48, p
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1027 CYTOMEGALOVIRUS (CMV) SEROLOGY IN SUDDEN INFANT DEATH SYNDROME (SIDS): LACK OF CORRELATION WITH CHLAMYDIA TRACHOMATIS SEROLOGYWe found Chlamydia trachomatis (C.t.) seropositivity to be significantly more frequent in SIDS than living controls. Bec...
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