Glycolysis and AR expression as biomarkers

Nature

Glycolysis and AR expression as biomarkers"


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Assessing androgen receptor (AR) expression and glycolytic activity using PET–CT imaging could be useful for predicting the prognosis of patients with metastatic castration-resistant


prostate cancer (CRPC), say researchers.


Josef Fox and co-workers enrolled 133 patients with progressive metastatic CRPC to undergo dual PET–CT imaging using 18F-fluorodeoxyglucose (18F-FDG) as an indicator of tumour glycolysis and


18F-fluorodihydrotestosterone (18F-FDHT) as an indicator of AR expression.


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