What is behavioral variant frontotemporal dementia?

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What is behavioral variant frontotemporal dementia?"


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In an era of etiology-specific therapies, defining the criteria for behavioral variant frontotemporal dementia is essential. How do we determine whether bad manners, laziness, or unsolicited


friendliness represents the earliest presentation of this condition? Diagnostic criteria are being actively evaluated to help establish a foundation for diagnostic decisions regarding this


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Read our FAQs * Contact customer support REFERENCES * Neary, D. _ et al_. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. _Neurology_ 51, 1546–1554 (1998).


Article  CAS  Google Scholar  * Rascovsky, K. _ et al_. Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions.


_Alzheimer Dis. Assoc. Disord._ 21, 514–518 (2007). Article  Google Scholar  * Piguet, O., Hornberger, M., Shelley, B. P., Kipps, C. M. & Hodges, J. R. Sensitivity of current criteria


for the diagnosis of behavioral variant frontotemporal dementia. _Neurology_ 72, 732–737 (2009). Article  CAS  Google Scholar  * Mendez, M. F. & Perryman, K. M. Neuropsychiatric features


of frontotemporal dementia: evaluation of consensus criteria and review. _J. Neuropsychiatry Clin. Neurosci._ 14, 424–429 (2002). Article  Google Scholar  * Rosen, H. J. _ et al_. Utility


of clinical criteria in differentiating frontotemporal lobar degeneration (FTLD) from AD. _Neurology_ 58, 1608–1615 (2002). Article  Google Scholar  * Knibb, J. A., Xuereb, J. H., Patterson,


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decline in autopsy-defined frontotemporal lobar degeneration. _Neurology_ 70, 2036–2045 (2008). Article  CAS  Google Scholar  * Forman, M. S. _ et al_. Frontotemporal dementia:


clinicopathological correlations. _Ann. Neurol._ 59, 952–962 (2006). Article  Google Scholar  * Knopman, D. S. _ et al_. Antemortem diagnosis of frontotemporal lobar degeneration. _Ann.


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1611–1616 (2007). Article  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Neurology, University of Pennsylvania School of Medicine,


Philadelphia, PA, USA Murray Grossman Authors * Murray Grossman View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to


Murray Grossman. ETHICS DECLARATIONS COMPETING INTERESTS M. Grossman has received research support from the NIH and has acted as a consultant for Allon Pharmaceutical. RIGHTS AND PERMISSIONS


Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Grossman, M. What is behavioral variant frontotemporal dementia?. _Nat Rev Neurol_ 5, 358–359 (2009).


https://doi.org/10.1038/nrneurol.2009.81 Download citation * Issue Date: July 2009 * DOI: https://doi.org/10.1038/nrneurol.2009.81 SHARE THIS ARTICLE Anyone you share the following link with


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