Assessing and improving the health-related quality of life of patients with esrd

Nature

Assessing and improving the health-related quality of life of patients with esrd"


Play all audios:

Loading...

ABSTRACT Impairment of the health-related quality of life (HRQOL) of patients with end-stage renal disease (ESRD) is now well documented. These impairments involve a wide variety of domains


and can be assessed using an array of well-validated instruments. Incorporation of at least some of these instruments into routine patient care is important in order to measure the physical


and psychological impact of a disease and its treatment on the HRQOL of patients. How this implementation can be achieved in a practical way is, however, a challenge. As more research


focuses on improving the HRQOL of patients with ESRD, the systematic evaluation of HRQOL and incorporation into patient care is becoming increasingly important. Whether strategies to improve


the HRQOL of patients will translate into improved patient outcomes—as evidenced by reduced mortality and hospitalizations—and lower costs, remains to be determined. KEY POINTS * The


assessment of health-related quality of life provides important information about patients with end-stage renal disease (ESRD) * Routine assessment of patient-reported outcomes (PROs) should


be incorporated into the standard care of patients with ESRD * Improvements in PROs can result from various interventions, such as treatment of depression and alterations in the dialysis


therapy regimen * Whether treatment algorithms designed to improve PROs will reduce rates of mortality and hospitalization remains to be determined Access through your institution Buy or


subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online


access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which


are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS


RAPID DECLINE IN KIDNEY FUNCTION IS ASSOCIATED WITH RAPID DETERIORATION OF HEALTH-RELATED QUALITY OF LIFE IN CHRONIC KIDNEY DISEASE Article Open access 31 January 2023 HEALTH-RELATED


QUALITY OF LIFE OF CHINESE PATIENTS WITH CHRONIC KIDNEY DISEASE: A STUDY BASED ON FOUR EQ-5D-3L VALUE SETS Article Open access 15 May 2023 THE IMPACT OF NUTRITIONAL STATUS ON HEALTH-RELATED


QUALITY OF LIFE IN HEMODIALYSIS PATIENTS Article Open access 22 February 2022 REFERENCES * Finkelstein, F. O., Wuerth, D. & Finkelstein, S. H. Health related quality of life and the CKD


patient: challenges for the nephrology community. _Kidney Int._ 76, 946–952 (2009). Article  PubMed  Google Scholar  * Evans, R. W. _ et al_. The quality of life of patients with end-stage


renal disease. _N. Engl. J. Med._ 312, 553–559 (1985). Article  CAS  PubMed  Google Scholar  * Boateng, E. A. & East, L. The impact of dialysis modality on quality of life: a systematic


review. _J. Ren. Care_ 37, 190–200 (2011). Article  PubMed  Google Scholar  * Mucsi, I., Kovacs, A. Z., Molnar, M. Z. & Novak, M. Co-morbidity and quality of life in chronic kidney


disease patients. _J. Nephrol._ 21 (Suppl. 13), S84–S91 (2008). PubMed  Google Scholar  * Glover, C., Banks, P., Carson, A., Martin, C. R. & Duffy, T. Understanding and assessing the


impact of end-stage renal disease on quality of life: a systematic review of the content validity of self-administered instruments used to assess health-related quality of life in end-stage


renal disease. _Patient_ 4, 19–30 (2011). Article  PubMed  Google Scholar  * Soni, R. K., Porter, A. C., Lash, J. P. & Unruh, M. L. Health-related quality of life in hypertension,


chronic kidney disease, and coexistent chronic health conditions. _Adv. Chronic Kidney Dis._ 17, e17–e26 (2010). Article  PubMed  PubMed Central  Google Scholar  * Landreneau, K., Lee, K.


& Landreneau, M. D. Quality of life in patients undergoing hemodialysis and renal transplantation—a meta-analytic review. _Nephrol. Nurs. J._ 37, 37–44 (2010). PubMed  Google Scholar  *


Soni, R. K., Weisbord, S. D. & Unruh, M. L. Health-related quality of life outcomes in chronic kidney disease. _Curr. Opin. Nephrol. Hypertens._ 19, 153–159 (2010). Article  CAS  PubMed


  PubMed Central  Google Scholar  * Germain, M. J. & Cohen, L. M. Maintaining quality of life at the end of life in the end-stage renal disease population. _Adv. Chronic Kidney Dis._ 15,


133–139 (2008). Article  PubMed  Google Scholar  * Weisbord, S. D. & Kimmel, P. L. Health-related quality of life in the era of erythropoietin. _Hemodial. Int._ 12, 6–15 (2008). Article


  PubMed  Google Scholar  * Dale, P. L., Hutton, J. & Elgazzar, H. Utility of health states in chronic kidney disease: a structured review of the literature. _Curr. Med. Res. Opin._ 24,


193–206 (2008). Article  CAS  PubMed  Google Scholar  * Clement, F. M., Klarenbach, S., Tonelli, M., Johnson, J. A. & Manns, B. J. The impact of selecting a high hemoglobin target level


on health-related quality of life for patients with chronic kidney disease: a systematic review and meta-analysis. _Arch. Intern. Med._ 169, 1104–1112 (2009). Article  CAS  PubMed  Google


Scholar  * Kimmel, P. L., Cohen, S. D. & Weisbord, S. D. Quality of life in patients with end-stage renal disease treated with hemodialysis: survival is not enough! _J. Nephrol._ 21


(Suppl. 13), S54–S58 (2008). PubMed  Google Scholar  * Unruh, M. L. & Hess, R. Assessment of health-related quality of life among patients with chronic kidney disease. _Adv. Chronic


Kidney Dis._ 14, 345–352 (2007). Article  PubMed  Google Scholar  * Korevaar, J. C. _ et al_. Validation of the KDQOL-SF: a dialysis-targeted health measure. _Qual. Life Res._ 11, 437–447


(2002). Article  CAS  PubMed  Google Scholar  * Steele, T. E. _ et al_. Sexual experience of the chronic peritoneal dialysis patient. _J. Am. Soc. Nephrol._ 7, 1165–1168 (1996). CAS  PubMed


  Google Scholar  * Peng, Y. S. _ et al_. Sexual dysfunction in female hemodialysis patients: a multicenter study. _Kidney Int._ 68, 760–765 (2005). Article  PubMed  Google Scholar  * Türk,


S. _ et al_. Quality of life in male hemodialysis patients. Role of erectile dysfunction. _Nephron Clin. Pract._ 96, c21–c27 (2004). Article  PubMed  Google Scholar  * Davison, S. N. The


prevalence and management of chronic pain in end-stage renal disease. _J. Palliat. Med._ 10, 1277–1287 (2007). Article  PubMed  Google Scholar  * Shayamsunder, A. K., Patel, S. S., Jain, V.,


Peterson, R. A. & Kimmel, P. L. Sleepiness, sleeplessness, and pain in end-stage renal disease: distressing symptoms for patients. _Semin. Dial._ 18, 109–118 (2005). Article  PubMed 


Google Scholar  * Cohen, S. D. _ et al_. Social support and chronic kidney disease: an update. _Adv. Chronic Kidney Dis._ 14, 335–344 (2007). Article  PubMed  Google Scholar  * Steele, T.


E., Finkelstein, S. H. & Finkelstein, F. O. Marital discord, sexual problems, and depression. _J. Nerv. Ment. Dis._ 162, 225–237 (1976). Article  CAS  PubMed  Google Scholar  * Steidl,


J. H. _ et al_. Medical condition, adherence to treatment regimens, and family functioning. Their interactions in patients receiving long-term dialysis treatment. _Arch. Gen. Psychiatry_ 37,


1025–1027 (1980). Article  CAS  PubMed  Google Scholar  * Fukuhara, S., Yamazaki, S., Hayashino, Y. & Green, J. Measuring health-related quality of life in patients with end-stage renal


disease: why and how. _Nat. Clin. Pract. Nephrol._ 3, 352–353 (2007). Article  PubMed  Google Scholar  * Hedayati, S. S. _ et al_. Death or hospitalization of patients on chronic


hemodialysis is associated with a physician-based diagnosis of depression. _Kidney Int._ 74, 930–936 (2008). Article  PubMed  Google Scholar  * Hedayati, S. S. _ et al_. Physician-diagnosed


depression as a correlate of hospitalizations in patients receiving long-term hemodialysis. _Am. J. Kidney Dis._ 46, 642–649 (2005). Article  PubMed  Google Scholar  * Lopes, A. A. _ et al_.


Screening for depression in hemodialysis patients: associations with diagnosis, treatment, and outcomes in the DOPPS. _Kidney Int._ 66, 2047–2053 (2004). Article  PubMed  Google Scholar  *


Lopes, A. A. _ et al_. for the Dialysis Outcomes and Practice Patterns Study (DOPPS). Depression as a predictor of mortality and hospitalization among hemodialysis patients in the United


States and Europe. _Kidney Int._ 62, 199–207 (2002). Article  PubMed  Google Scholar  * Kutner, N. G., Zhang, R., Barnhart, H. & Collins, A. J. Health status and quality of life reported


by incident patients after 1 year on haemodialysis or peritoneal dialysis. _Nephrol. Dial. Transplant._ 20, 2159–2167 (2005). Article  PubMed  Google Scholar  * Kutner, N. G. Quality of


life and daily hemodialysis. _Semin. Dial._ 17, 92–98 (2004). Article  PubMed  Google Scholar  * Mapes, D. L. _ et al_. Health-related quality of life as a predictor of mortality and


hospitalization: the Dialysis Outcomes and Practice Patterns Study (DOPPS). _Kidney Int._ 64, 339–349 (2003). Article  PubMed  Google Scholar  * Wu, A. W. _ et al_. Changes in quality of


life during hemodialysis and peritoneal dialysis treatment: generic and disease specific measures. _J. Am. Soc. Nephrol._ 15, 743–753 (2004). Article  PubMed  Google Scholar  * Kimmel, P.


L., Emont, S. L., Newmann, J. M., Danko, H. & Moss, A. H. ESRD patient quality of life: symptoms, spiritual beliefs, psychosocial factors, and ethnicity. _Am. J. Kidney Dis._ 42, 713–721


(2003). Article  PubMed  Google Scholar  * Kimmel, P. L. _ et al_. Multiple measurements of depression predict mortality in a longitudinal study of chronic hemodialysis outpatients. _Kidney


Int._ 57, 2093–2098 (2000). Article  CAS  PubMed  Google Scholar  * Reynolds, J. T. _ et al_. A one-year trial of in-center daily hemodialysis with an emphasis on quality of life. _Blood


Purif._ 22, 320–328 (2004). Article  PubMed  Google Scholar  * Lacson, E. Jr _ et al_. Depressive symptoms associate with high mortality risk and dialysis withdrawal in incident hemodialysis


patients. _Nephrol. Dial. Transplant._ 27, 2921–2928 (2012). Article  PubMed  Google Scholar  * Jaber, B. L. _ et al_. on behalf of the FREEDOM Study Group. Impact of short daily


hemodialysis on restless legs symptoms and sleep disturbances. _Clin. J. Am. Soc. Nephrol._ 6, 1049–1056 (2011). Article  PubMed  PubMed Central  Google Scholar  * Jaber, B. L. _ et al_.


Effect of daily hemodialysis on depressive symptoms and postdialysis recovery time: interim report from the FREEDOM (Following Rehabilitation, Economics and Everyday-Dialysis Outcome


Measurements) Study. _Am. J. Kidney Dis._ 56, 531–539 (2010). Article  PubMed  Google Scholar  * Finkelstein, F. O. _ et al_. At-home short daily hemodialysis improves the long-term


health-related quality of life. _Kidney Int._ 82, 561–569 (2012). Article  PubMed  Google Scholar  * Brown, E. A. Can quality of life be improved for the increasing numbers of older patients


with end-stage kidney disease? _Expert Rev. Pharmacoecon. Outcomes Res._ 10, 661–666 (2010). Article  PubMed  Google Scholar  * Kliger, A. S. & Finkelstein, F. O. Can we improve the


quality of life for dialysis patients? _Am. J. Kidney Dis._ 54, 993–995 (2009). Article  PubMed  Google Scholar  * Chertow, G. M. _ et al_. In-center hemodialysis six times per week versus


three times per week. _N. Engl. J. Med._ 363, 2287–2300 (2010). Article  CAS  PubMed  Google Scholar  * Duarte, P. S., Miyazaki, M. C., Blay, S. L. & Sesso, R. Cognitive-behavioral group


therapy is an effective treatment for major depression in hemodialysis patients. _Kidney Int._ 76, 414–421 (2009). Article  PubMed  Google Scholar  * Painter, P. _ et al_. Effects of


exercise training plus normalization of hematocrit on exercise capacity and health-related quality of life. _Am. J. Kidney Dis._ 39, 257–265 (2002). Article  PubMed  Google Scholar  * Suri,


R. S. _ et al_. for the Frequent Hemodialysis Network Trial Group. Frequent Hemodialysis Network (FHN) randomized trials: study design. _Kidney Int._ 71, 349–359 (2007). Article  CAS  PubMed


  Google Scholar  * U. S. Department of Health and Human Services. Guidance for industry patient-reported outcome measures: use in medical product development to support labeling claims


[online], (2009). * Jaber, B. L. _ et al_. Scope and design of the Following Rehabilitation, Economics and Everyday-Dialysis Outcome Measurements (FREEDOM) Study. _Am. J. Kidney Dis._ 53,


310–320 (2009). Article  PubMed  Google Scholar  * National Institutes of Health. PROMIS®: Dynamic tools to measure health outcomes from the patient perspective [online], (2012). *


Patient-Centered Outcomes Research Institute. Patient-Centered Outcomes Research [online], (2012). * Kliger, A. S., Fishbane, S. & Finkelstein, F. O. Erythropoietic stimulating agents


and quality of a patient's life: individualizing anemia treatment. _Clin. J. Am. Soc. Nephrol._ 7, 354–357 (2012). Article  CAS  PubMed  Google Scholar  * Leaf, D. E. & Goldfarb, D.


S. Interpretation and review of health-related quality of life data in CKD patients receiving treatment for anemia. _Kidney Int._ 75, 15–24 (2009). Article  PubMed  Google Scholar  *


Johansen, K. L. _ et al_. Systematic review and meta-analysis of exercise tolerance and physical functioning in dialysis patients treated with erythropoiesis-stimulating agents. _Am. J.


Kidney Dis._ 55, 535–548 (2010). Article  CAS  PubMed  Google Scholar  * Gandra, S. R. _ et al_. Impact of erythropoiesis-stimulating agents on energy and physical function in nondialysis


CKD patients with anemia: a systematic review. _Am. J. Kidney Dis._ 55, 519–534 (2010). Article  CAS  PubMed  Google Scholar  * Weisbord, S. D. _ et al_. Renal provider recognition of


symptoms in patients on maintenance hemodialysis. _Clin. J. Am. Soc. Nephrol._ 2, 960–967 (2007). Article  PubMed  Google Scholar  * Brown, E. A. _ et al_. Broadening options for long-term


dialysis in the elderly (BOLDE): differences in quality of life on peritoneal dialysis compared to haemodialysis for older patients. _Nephrol. Dial. Transplant._ 25, 3755–3763 (2010).


Article  PubMed  PubMed Central  Google Scholar  * Paniagua, R., Amato, D., Vonesh, E., Guo, A. & Mujais, S. for the Mexican Nephrology Collaborative Study Group. Health-related quality


of life predicts outcomes but is not affected by peritoneal clearance: the ADEMEX trial. _Kidney Int._ 67, 1093–1104 (2005). Article  PubMed  Google Scholar  * Balducci, L. Death and dying:


what the patient wants. _Ann. Oncol._ 23 (Suppl. 3), 56–61 (2012). Article  PubMed  Google Scholar  * Martino, S., Chwastiak, L. & Finkelstein, F. O. in _Nutritional Management of Renal


Disease_ 3rd edn (eds Kopple, J. D., Massry, S. G. & Kalanter-Zadeh, K.) (Academic Press, Philadelphia, 2012, in press). Google Scholar  * Teutsch, C. Patient-doctor communication. _Med.


Clin. North Am._ 87, 1115–1145 (2003). Article  PubMed  Google Scholar  * Thong, M. S. _ et al_. Association between a self-rated health question and mortality in young and old dialysis


patients: a cohort study. _Am. J. Kidney Dis._ 52, 111–117 (2008). Article  PubMed  Google Scholar  * Cukor, D. _ et al_. Anxiety disorders in adults treated by hemodialysis: a single-center


study. _Am. J. Kidney Dis._ 52, 128–136 (2008). Article  PubMed  Google Scholar  * Juergensen, E. _ et al_. Hemodialysis and peritoneal dialysis: patients' assessment of their


satisfaction with therapy and the impact of the therapy on their lives. _Clin. J. Am. Soc. Nephrol._ 1, 1191–1196 (2006). Article  PubMed  Google Scholar  * Rubin, H. R. _ et al_. Patient


ratings of dialysis care with peritoneal dialysis vs hemodialysis. _JAMA_ 291, 697–703 (2004). Article  CAS  PubMed  Google Scholar  * Tong, A. _ et al_. Patients' priorities for health


research: focus group study of patients with chronic kidney disease. _Nephrol. Dial. Transplant._ 23, 3206–3214 (2008). Article  PubMed  Google Scholar  * Fadem, S. Z. _ et al_.


Satisfaction with renal replacement therapy and education: the American Association of Kidney Patients survey. _Clin. J. Am. Soc. Nephrol._ 6, 605–612 (2011). Article  PubMed  PubMed Central


  Google Scholar  * Al Eissa, M. _ et al_. Factors affecting hemodialysis patients' satisfaction with their dialysis therapy. _Int. J. Nephrol._ 2010, 342901 (2010). Article  CAS 


PubMed  PubMed Central  Google Scholar  * Gayomali, C., Sutherland, S. & Finkelstein, F. O. The challenge for the caregiver of the patient with chronic kidney disease. _Nephrol. Dial.


Transplant._ 23, 3749–3751 (2008). Article  PubMed  Google Scholar  * Unruh, M. _ et al_. Effects of hemodialysis dose and membrane flux on health-related quality of life in the HEMO Study.


_Kidney Int._ 66, 355–366 (2004). Article  PubMed  Google Scholar  * Cullerton, B. _ et al_. Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass


and quality of life: a randomized controlled trial. _JAMA_ 298, 1291–1299 (2007). Article  Google Scholar  * Manns, B. J. _ et al_. Nocturnal hemodialysis does not improve overall measures


of quality of life compared to conventional hemodialysis. _Kidney Int._ 75, 542–549 (2009). Article  PubMed  Google Scholar  * Unruh, M. L. _ et al_. Effects of six versus three times per


week hemodialysis on depressive affect and mental health: Frequent Hemodialysis Network (FHN) Trials [abstract]. _J. Am. Soc. Nephrol._ 22, TH-PO623 (2011). Google Scholar  * Butt, Z.,


Yount, S. E., Caicedo, J. C., Abecassis, M. M. & Cella, D. Quality of life assessment in renal transplant: review and future directions. _Clin. Transplant._ 22, 292–303 (2008). Article 


PubMed  Google Scholar  * Dobbels, F., De Bleser, L., De Geest, S. & Fine, R. N. Quality of life after kidney transplantation: the bright side of life? _Adv. Chronic Kidney Dis._ 14,


370–378 (2007). Article  PubMed  Google Scholar  * Maglakelidze, N., Pantsulaia, T., Tchokhonelidze, I., Managadze, L. & Chkhotua, A. Assessment of health-related quality of life in


renal transplant recipients and dialysis patients. _Transplant. Proc._ 43, 376–379 (2011). Article  CAS  PubMed  Google Scholar  * Bonney, S., Finkelstein, F. O., Lytton, B., Schiff, M.


& Steele, T. E. Treatment of end-stage renal failure in a defined geographic area. _Arch. Intern. Med._ 138, 1510–1513 (1978). Article  CAS  PubMed  Google Scholar  * Tonelli, M. _ et


al_. Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes. _Am. J. Transplant._ 11, 2093–2109 (2011). Article  CAS  PubMed  Google Scholar  *


Avramovic, M. & Stefanovic, V. Health-related quality of life in different stages of renal failure. _Artif. Organs_ 36, 581–589 (2012). Article  PubMed  Google Scholar  * Tong, A. _ et


al_. The motivations and experiences of living kidney donors: a thematic synthesis. _Am. J. Kidney Dis._ 60, 15–26 (2012). Article  PubMed  Google Scholar  * United States Census Bureau


[online], (2011). * United States Renal Data System. _2011 Annual Data Report_ [online], (2011). * Kadambi, P., Troidle, L., Gorban-Brennan, N., Kilger, A. S. & Finkelstein, F. O. APD in


the elderly. _Semin. Dial._ 15, 430–433 (2002). Article  PubMed  Google Scholar  * Davison, S. N. End-of-life care preferences and needs: perceptions of patients with chronic kidney


disease. _Clin. J. Am. Soc. Nephrol._ 5, 195–204 (2010). Article  PubMed  PubMed Central  Google Scholar  * Brown, E. A. & Johansson, L. Epidemiology and management of end-stage renal


disease in the elderly. _Nat. Rev. Nephrol._ 7, 591–598 (2011). Article  PubMed  Google Scholar  * Dimkovic, N. & Oreopoulos, D. Management of elderly patients with end-stage kidney


disease. _Semin. Nephrol._ 29, 643–649 (2009). Article  PubMed  Google Scholar  * Schmidt, R. J. Informing our elders about dialysis: is an age-attuned approach warranted? _Clin. J. Am. Soc.


Nephrol._ 7, 185–191 (2012). Article  PubMed  Google Scholar  * Chandna, S. M. _ et al_. Survival of elderly patients with stage 5 CKD: comparison of conservative management and renal


replacement therapy. _Nephrol. Dial. Transplant._ 26, 1608–1614 (2011). Article  PubMed  Google Scholar  * Murtagh, F. E. _ et al_. Dialysis or not? A comparative survival study of patients


over 75 years with chronic kidney disease stage 5. _Nephrol. Dial. Transplant._ 22, 1955–1962 (2007). Article  PubMed  Google Scholar  * Peterson, R. A. _ et al_. Depression, perception of


illness and mortality in patients with end-stage renal disease. _Int. J. Psychiatry Med._ 21, 343–354 (1991). Article  CAS  PubMed  Google Scholar  * Hedayati, S. S. & Finkelstein, F. O.


Epidemiology, diagnosis, and management of depression in patients with CKD. _Am. J. Kidney Dis._ 54, 741–752 (2009). Article  PubMed  PubMed Central  Google Scholar  * Boulware, L. E. _ et


al_. Temporal relation among depression symptoms, cardiovascular disease events, and mortality in end-stage renal disease: contribution of reverse causality. _Clin. J. Am. Soc. Nephrol._ 1,


496–504 (2006). Article  PubMed  Google Scholar  * Hedayati, S. S., Yalamanchili, V. & Finkelstein, F. O. A practical approach to the treatment of depression in patients with chronic


kidney disease and end-stage renal disease. _Kidney Int._ 81, 247–255 (2012). Article  PubMed  Google Scholar  * Ouzouni, S., Kouidi, E., Sioulis, A., Grekas, D. & Deligiannis, A.


Effects of intradialytic exercise training on health-related quality of life indices in haemodialysis patients. _Clin. Rehabil._ 23, 53–63 (2009). Article  PubMed  Google Scholar  *


Levendog˘lu, F. _ et al_. A twelve week exercise program improves the psychological status, quality of life and work capacity in hemodialysis patients. _J. Nephrol._ 17, 826–832 (2004).


Google Scholar  * Sprangers, M. A. _ et al_. The establishment of the GENEQOL consortium to investigate the genetic disposition of patient-reported quality-of-life outcomes. _Twin Res. Hum.


Genet._ 12, 301–311 (2009). Article  PubMed  PubMed Central  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Yale University School of Medicine, New Haven,


06510, CT, USA Fredric O. Finkelstein & Susan H. Finkelstein * Yale–New Haven Hospital, 20 York Street, New Haven, 06510, CT, USA Kelli L. Arsenault, Ana Taveras & Kwabena Awuah


Authors * Fredric O. Finkelstein View author publications You can also search for this author inPubMed Google Scholar * Kelli L. Arsenault View author publications You can also search for


this author inPubMed Google Scholar * Ana Taveras View author publications You can also search for this author inPubMed Google Scholar * Kwabena Awuah View author publications You can also


search for this author inPubMed Google Scholar * Susan H. Finkelstein View author publications You can also search for this author inPubMed Google Scholar CONTRIBUTIONS All authors


contributed equally to discussion of content for the article, researching data to include in the manuscript, and reviewing and editing of the manuscript before submission. CORRESPONDING


AUTHOR Correspondence to Fredric O. Finkelstein. ETHICS DECLARATIONS COMPETING INTERESTS F. Finkelstein is a consultant and has received grant or research support from Amjen. He is on the


speakers bureau for Baxter and is a consultant for NxStage Medical. F. Finkelstein, K. L. Arsenault, A. Taveras and K. Awuah are affiliated with New Haven Home Dialysis, which is owned by


Fresenius Medical Care. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Finkelstein, F., Arsenault, K., Taveras, A. _et al._ Assessing and improving the


health-related quality of life of patients with ESRD. _Nat Rev Nephrol_ 8, 718–724 (2012). https://doi.org/10.1038/nrneph.2012.238 Download citation * Published: 23 October 2012 * Issue


Date: December 2012 * DOI: https://doi.org/10.1038/nrneph.2012.238 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a


shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative


Trending News

allopen3 | designboom.com

* imprint * privacy policy * terms of use * cookies * copyright info * contribute * about us * contact us * newsletter *...

Something went wrong, sorry. :(

The Paris mairie is cracking down on ‘voyeurs’ and similar sexual assaults in its public swimming pools, after many wome...

Raft of fines handed out on one road near welsh beach

THEY WERE PARKED ON A SINGLE YELLOW LINE WITH SOME SAYING IT'S 'NOT CLEAR' YOU CAN'T PARK THERE RICH...

Volunteer Or Donate | VA Cincinnati Health Care | Veterans Affairs

Volunteer or donate VA Cincinnati Healthcare System depends on the goodwill of our supporters. You can make a difference...

Bethenny frankel says she's 'still married' to ex jason hoppy nearly 8 years after filing for divorce

Bethenny Frankel says she's "still married" to ex Jason Hoppy, despite separating almost eight years ago....

Latests News

Assessing and improving the health-related quality of life of patients with esrd

ABSTRACT Impairment of the health-related quality of life (HRQOL) of patients with end-stage renal disease (ESRD) is now...

'The Hitman's Bodyguard' Movie Trailer

1:59 AARP Videos Entertainment 'The Hitman's Bodyguard' Movie Trailer The world's top bodyguard gets a new client, a hit...

Google introduces 'circle to search,' a new way to search from anywhere on android using gestures | techcrunch

Alongside Samsung’s launch event today, Google announced a new way to search on Android phones dubbed “Circle to Search....

Max mosley, oxford and the corrosion of academic integrity | thearticle

What if… a major British political party were shown to have received contributions amounting to nearly £12.4 million fro...

Personal Finance - Advice and News for the 50+

Personal Finance From building wealth to bargain hunting, great ideas to sharpen your money management skills 10 Easy Fi...

Top