Wrestling with filaments | Nature Reviews Molecular Cell Biology

Access through your institution Buy or subscribe Using a proteomic screen in _Caenorhabditis elegans_, Kaminsky _et al_. identified a group of intermediate filament proteins as putative

targets of the small ubiquitin-related modifier (SUMO), SMO-1. To investigate this possible link between sumoylation and filament assembly, the authors focused on IFB-1A, which links the

apical and basal hemidesmosome-like structures of the epidermis and is essential for embryonic elongation and maintenance of muscle attachment to the cuticle. > “Sumoylation of IFB-1A 

occurs at the C terminus and regulates the > assembly of IFB-1A into epidermal filaments” This is a preview of subscription content, access via your institution ACCESS OPTIONS Access

through your institution Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink *

Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional

subscriptions * Read our FAQs * Contact customer support REFERENCES ORIGINAL RESEARCH PAPER * Kaminsky, R. et al. SUMO regulates the assembly and function of a cytoplasmic intermediate

filament protein in _C. elegans_. _Dev. Cell_ 17, 724–735 (2009). Article  CAS  Google Scholar  FURTHER READING * Geiss-Friedlander, R. & Melchior, F. Concepts in sumoylation: a decade

on. _Nature Rev. Mol. Cell Biol._ 8, 947–956 (2007). Article  CAS  Google Scholar  Download references Authors * Debbie Walker View author publications You can also search for this author

inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Walker, D. Wrestling with filaments. _Nat Rev Mol Cell Biol_ 11, 3 (2010).

https://doi.org/10.1038/nrm2823 Download citation * Published: 09 December 2009 * Issue Date: January 2010 * DOI: https://doi.org/10.1038/nrm2823 SHARE THIS ARTICLE Anyone you share the

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