Disease and comorbidity—effects on quality of life
Disease and comorbidity—effects on quality of life"
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Nonalcoholic fatty liver disease has long been neglected by health-care professionals unless affected patients develop cirrhosis; however, new research shows this disease impairs
health-related quality of life. The association of nonalcoholic fatty liver disease with chronic metabolic diseases and cardiovascular complications restricts our ability to define a
specific role for liver damage in the poor perceived health status of these patients. Access through your institution Buy or subscribe This is a preview of subscription content, access via
your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this
article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in
* Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Ekstedt, M. _ et al_. Long-term follow-up of patients with NAFLD and elevated liver
enzymes. _Hepatology_ 44, 865–873 (2006). Article CAS Google Scholar * Marchesini, G. _ et al_. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. _Hepatology_ 37,
917–923 (2003). Article Google Scholar * David, K. _ et al_. Quality of life in adults with nonalcoholic fatty liver disease: baseline data from the nonalcoholic steatohepatitis clinical
research network. _Hepatology_ 49, 1904–1912 (2009). Article Google Scholar * Ware, J. E. Jr, Snow, K., Kosinski, M. & Gandek, B. _SF-36 Health Survey Manual and Interpretation Guide_
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disease-specific quality-of-life measures in patients with NIDDM. _Diabetes Care_ 20, 299–305 (1997). Article CAS Google Scholar * Marchesini, G. _ et al_. Factors associated with poor
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factors reduce health-related quality of life in hepatitis C virus infection. _Gut_ 57, 1597–1603 (2008). Article CAS Google Scholar * Newton, J. L. _ et al_. Fatigue in non-alcoholic
fatty liver disease (NAFLD) is significant and associates with inactivity and excessive daytime sleepiness but not with liver disease severity or insulin resistance. _Gut_ 57, 807–813
(2008). Article CAS Google Scholar * Dan, A. A. _ et al_. Health-related quality of life in patients with non-alcoholic fatty liver disease. _Aliment. Pharmacol. Ther._ 26, 815–820
(2007). Article CAS Google Scholar Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Clinical Dietetics, “Alma Mater Studiorum” University, Bologna, Italy
Giulio Marchesini * Department of Internal Medicine, “Alma Mater Studiorum” University, Bologna, Italy Giampaolo Bianchi Authors * Giulio Marchesini View author publications You can also
search for this author inPubMed Google Scholar * Giampaolo Bianchi View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to
Giulio Marchesini. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing financial interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS
ARTICLE Marchesini, G., Bianchi, G. Disease and comorbidity—effects on quality of life. _Nat Rev Gastroenterol Hepatol_ 6, 504–506 (2009). https://doi.org/10.1038/nrgastro.2009.142 Download
citation * Issue Date: September 2009 * DOI: https://doi.org/10.1038/nrgastro.2009.142 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get
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