Circadiomics: integrating circadian genomics, transcriptomics, proteomics and metabolomics

Access through your institution Buy or subscribe To the Editor: Circadian rhythms govern a large array of physiological and metabolic functions1. It is critical to decode circadian

oscillations by integrating multiple 'omic' approaches. Circadian genomic and transcriptomic data sets are accessible, and recently, metabolomics data in the circadian context also

have been made available2. The components for building a comprehensive map of circadian networks are thus ready for assembly. This is a preview of subscription content, access via your

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article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in

* Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Eckel-Mahan, K. & Sassone-Corsi, P. _Nat. Struct. Mol. Biol._ 16, 462–467 (2009).

Article  CAS  Google Scholar  * Eckel-Mahan, K.L. et al. _Proc. Natl. Acad. Sci. USA_ 109, 5541–5546 (2012). Article  CAS  Google Scholar  * Kanehisa, M. & Goto, S. _Nucleic Acids Res._

28, 27–30 (2000). Article  CAS  Google Scholar  * Hughes, M.E. et al. _PLoS Genet._ 5, e1000442 (2009). Article  Google Scholar  * Xie, X., Rigor, P. & Baldi, P. _Bioinformatics_ 25,

167–174 (2009). Article  CAS  Google Scholar  * Baker, M. _Nat. Methods_ 8, 117–121 (2011). Article  CAS  Google Scholar  Download references ACKNOWLEDGEMENTS We thank J. Hayes for helping

with the development and deployment of the web server. This work was supported by US National Institutes of Health (NIH) National Research Service Award F32 DK083881 (to K.E.-M.), NIH

GM081634 and AG033888 (to P.S.-C.), Sirtris Pharmaceuticals SP-48984 (to P.S.-C.), National Science Foundation IIS-0513376 (to P.B.), NIH LM010235 (to P.B.) and NIH National Library of

Medicine T15 LM07443 (to P.B.). AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Computer Science, University of California, Irvine (UCI), Irvine, California, USA Vishal R Patel 

& Pierre Baldi * Institute for Genomics and Bioinformatics, UCI, Irvine, California, USA Vishal R Patel, Paolo Sassone-Corsi & Pierre Baldi * Department of Biological Chemistry, UCI,

Irvine, California, USA Kristin Eckel-Mahan, Paolo Sassone-Corsi & Pierre Baldi * Center for Epigenetics and Metabolism, UCI, Irvine, California, USA Kristin Eckel-Mahan, Paolo

Sassone-Corsi & Pierre Baldi Authors * Vishal R Patel View author publications You can also search for this author inPubMed Google Scholar * Kristin Eckel-Mahan View author publications

You can also search for this author inPubMed Google Scholar * Paolo Sassone-Corsi View author publications You can also search for this author inPubMed Google Scholar * Pierre Baldi View

author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHORS Correspondence to Paolo Sassone-Corsi or Pierre Baldi. ETHICS DECLARATIONS COMPETING

INTERESTS The authors declare no competing financial interests. SUPPLEMENTARY INFORMATION SUPPLEMENTARY TEXT AND FIGURES Supplementary Figures 1 and 2 and Supplementary Methods (PDF 689 kb)

RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Patel, V., Eckel-Mahan, K., Sassone-Corsi, P. _et al._ CircadiOmics: integrating circadian genomics,

transcriptomics, proteomics and metabolomics. _Nat Methods_ 9, 772–773 (2012). https://doi.org/10.1038/nmeth.2111 Download citation * Published: 30 July 2012 * Issue Date: August 2012 * DOI:

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