Circadiomics: integrating circadian genomics, transcriptomics, proteomics and metabolomics

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Circadiomics: integrating circadian genomics, transcriptomics, proteomics and metabolomics"


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Access through your institution Buy or subscribe To the Editor: Circadian rhythms govern a large array of physiological and metabolic functions1. It is critical to decode circadian


oscillations by integrating multiple 'omic' approaches. Circadian genomic and transcriptomic data sets are accessible, and recently, metabolomics data in the circadian context also


have been made available2. The components for building a comprehensive map of circadian networks are thus ready for assembly. This is a preview of subscription content, access via your


institution RELEVANT ARTICLES Open Access articles citing this article. * THE HIDDEN LINK BETWEEN CIRCADIAN ENTROPY AND MENTAL HEALTH DISORDERS * Amal Alachkar * , Justine Lee *  … Pierre


Baldi _Translational Psychiatry_ Open Access 14 July 2022 * COCAINE-MEDIATED CIRCADIAN REPROGRAMMING IN THE STRIATUM THROUGH DOPAMINE D2R AND PPARΓ ACTIVATION * Karen Brami-Cherrier * ,


Robert G. Lewis *  … Emiliana Borrelli _Nature Communications_ Open Access 07 September 2020 * THE MYC TRANSCRIPTION FACTOR NETWORK: BALANCING METABOLISM, PROLIFERATION AND ONCOGENESIS *


Patrick A. Carroll * , Brian W. Freie *  … Robert N. Eisenman _Frontiers of Medicine_ Open Access 27 July 2018 ACCESS OPTIONS Access through your institution Subscribe to this journal


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REFERENCES * Eckel-Mahan, K. & Sassone-Corsi, P. _Nat. Struct. Mol. Biol._ 16, 462–467 (2009). Article  CAS  Google Scholar  * Eckel-Mahan, K.L. et al. _Proc. Natl. Acad. Sci. USA_ 109,


5541–5546 (2012). Article  CAS  Google Scholar  * Kanehisa, M. & Goto, S. _Nucleic Acids Res._ 28, 27–30 (2000). Article  CAS  Google Scholar  * Hughes, M.E. et al. _PLoS Genet._ 5,


e1000442 (2009). Article  Google Scholar  * Xie, X., Rigor, P. & Baldi, P. _Bioinformatics_ 25, 167–174 (2009). Article  CAS  Google Scholar  * Baker, M. _Nat. Methods_ 8, 117–121


(2011). Article  CAS  Google Scholar  Download references ACKNOWLEDGEMENTS We thank J. Hayes for helping with the development and deployment of the web server. This work was supported by US


National Institutes of Health (NIH) National Research Service Award F32 DK083881 (to K.E.-M.), NIH GM081634 and AG033888 (to P.S.-C.), Sirtris Pharmaceuticals SP-48984 (to P.S.-C.), National


Science Foundation IIS-0513376 (to P.B.), NIH LM010235 (to P.B.) and NIH National Library of Medicine T15 LM07443 (to P.B.). AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of


Computer Science, University of California, Irvine (UCI), Irvine, California, USA Vishal R Patel & Pierre Baldi * Institute for Genomics and Bioinformatics, UCI, Irvine, California, USA


Vishal R Patel, Paolo Sassone-Corsi & Pierre Baldi * Department of Biological Chemistry, UCI, Irvine, California, USA Kristin Eckel-Mahan, Paolo Sassone-Corsi & Pierre Baldi * Center


for Epigenetics and Metabolism, UCI, Irvine, California, USA Kristin Eckel-Mahan, Paolo Sassone-Corsi & Pierre Baldi Authors * Vishal R Patel View author publications You can also


search for this author inPubMed Google Scholar * Kristin Eckel-Mahan View author publications You can also search for this author inPubMed Google Scholar * Paolo Sassone-Corsi View author


publications You can also search for this author inPubMed Google Scholar * Pierre Baldi View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING


AUTHORS Correspondence to Paolo Sassone-Corsi or Pierre Baldi. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing financial interests. SUPPLEMENTARY INFORMATION


SUPPLEMENTARY TEXT AND FIGURES Supplementary Figures 1 and 2 and Supplementary Methods (PDF 689 kb) RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE


Patel, V., Eckel-Mahan, K., Sassone-Corsi, P. _et al._ CircadiOmics: integrating circadian genomics, transcriptomics, proteomics and metabolomics. _Nat Methods_ 9, 772–773 (2012).


https://doi.org/10.1038/nmeth.2111 Download citation * Published: 30 July 2012 * Issue Date: August 2012 * DOI: https://doi.org/10.1038/nmeth.2111 SHARE THIS ARTICLE Anyone you share the


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