Cd8: from coreceptor to comodulator

Conventional CD8αβ participates in the activation of T cells by binding to the same peptide-MHC complex as does the TCR. A recent paper in _Science_ shows, however, that the CD8αα form on

iIELs binds TL and could alter signals from the TCR. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution RELEVANT ARTICLES

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_Adv. Immunol._ 76, 1–60 (2001). Article  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * INSERM U463, Institut de Biologie, Nantes, France Marc Bonneville 

& François Lang Authors * Marc Bonneville View author publications You can also search for this author inPubMed Google Scholar * François Lang View author publications You can also

search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Bonneville, M., Lang, F. CD8: from coreceptor to

comodulator. _Nat Immunol_ 3, 12–14 (2002). https://doi.org/10.1038/ni0102-12 Download citation * Issue Date: 01 January 2002 * DOI: https://doi.org/10.1038/ni0102-12 SHARE THIS ARTICLE

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