Virus hope for diabetics | Nature

Access through your institution Buy or subscribe Diabetic rats go into remission five days after being given a new gene, paving the way for clinical trials of the therapy. If effective in

humans, this gene therapy would mean the end of frequent insulin injections and occasional dangerous comas for diabetes sufferers. Ji-Won Yoon at Yonsei University, Seoul, Korea, and his

colleagues have cured rats with diabetes by engineering them to produce a reasonably efficient insulin analogue - and, crucially, to produce it in response the levels of glucose in their

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are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Lee, H. C., Kim, S.-J.,

Kim, K.-S., Shin, H.-C. & Yoon, J.-W. Remission in models of type I diabetes by gene therapy using a single-chain insulin analogue. _Nature_ 408, 483-488 (2000). Article  ADS  CAS 

Google Scholar  Download references Authors * Valerie Depraetere View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and

permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Depraetere, V. Virus hope for diabetics. _Nature_ (2000). https://doi.org/10.1038/news001123-9 Download citation * Published: 23 November

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