Chondrocalcinosis does not worsen cartilage loss in knee OA

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Chondrocalcinosis does not worsen cartilage loss in knee OA"


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Neogi T et al. (2006) Lack of association between chondrocalcinosis and increased risk of cartilage loss in knees with osteoarthritis: results of two prospective longitudinal magnetic


resonance imaging studies. Arthritis Rheum 54: 1822–1828


Chondrocalcinosis (the deposition of calcium pyrophosphate dihydrate crystals in hyaline articular and/or meniscal fibrocartilage) is not associated with cartilage loss in osteoarthritic


knees, say Neogi et al. Their finding is not new, but is important, as concerns about the sensitivity of radiographic detection of cartilage loss brought the findings of earlier, similar


studies into question.


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