Translational synthetic chemistry

Providing chemical matter to modulate newly identified biological targets—as well as pre-existing but chemically intractable ones—remains a challenge in the discovery of therapeutics. Here,

we discuss opportunities for synthetic chemists to make a direct impact in addressing targets that are considered 'undruggable'. Access through your institution Buy or subscribe

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calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Austad, B.C. et al. _Synlett_

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Acad. Sci. USA_ 108, 6817–6822 (2011). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Sarathy Kesavan and Lisa A. Marcaurelle are at H3

Biomedicine Inc., Cambridge, Massachusetts, USA., Sarathy Kesavan & Lisa A Marcaurelle Authors * Sarathy Kesavan View author publications You can also search for this author inPubMed 

Google Scholar * Lisa A Marcaurelle View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Lisa A Marcaurelle. ETHICS

DECLARATIONS COMPETING INTERESTS The authors declare no competing financial interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Kesavan, S.,

Marcaurelle, L. Translational synthetic chemistry. _Nat Chem Biol_ 9, 210–213 (2013). https://doi.org/10.1038/nchembio.1207 Download citation * Published: 18 March 2013 * Issue Date: April

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