Group-specific component (gc) polymorphism in japanese: an investigation on the phenotypic distribution with regard to thegc j allele

Nature

Group-specific component (gc) polymorphism in japanese: an investigation on the phenotypic distribution with regard to thegc j allele"


Play all audios:

Loading...

SUMMARY Using the prolonged immunoelectrophoresis, Gc determination was performed in 1,347 plasma collected from 3 local populations in Japan. Six phenotypes determined by the codominant


alleles,_Gc_ 1,_Gc_ 2 and_Gc_ J, were observed, in which a new phenotype GcJ-J was included. This study revealed the presence of at least 3 polymorphic alleles at Gc locus in Japanese


population. SIMILAR CONTENT BEING VIEWED BY OTHERS RAPID DETECTION OF PHENOTYPES BOMBAY _SE__DEL_ AND NONSECRETOR RS200157007 SNP (302C > T) BY REAL-TIME PCR-BASED METHODS Article Open


access 22 July 2021 MULTIPLEX-PCR TECHNIQUE TO PREDICT POLYMORPHIC ANTIGENS – M, N, S AND S – AND ASSOCIATIONS BETWEEN THEIR ALLELES AND MIA-ASSOCIATED HYBRID GLYCOPHORINS Article Open


access 22 January 2025 INVESTIGATION OF BLOOD GROUP GENOTYPE PREVALENCE IN KOREAN POPULATION USING LARGE GENOMIC DATABASES Article Open access 15 September 2023 ARTICLE PDF REFERENCES *


Cleve, H. 1973. The variants of the group-specific component._Isr. J. Med. Sci._ 9: 1133–1146. CAS  PubMed  Google Scholar  * Cleve, H., Kirk, R. L., Parlcer, W. C., Bearn, A. G., Schacht,


L. E., Kleinman, H., and Horsfall, W. R. 1963. Two genetic variants of the group-specific component of human serum: Gc Chippewa and Gc Aborigine._Am. J. Hum. Genet._ 15: 368–379. CAS  PubMed


  PubMed Central  Google Scholar  * Constans, J. and Viau, M. 1977. Group-specific component: Evidence for two subtypes of the Gc gene._Science_,198: 1070–1071. Article  CAS  PubMed  Google


Scholar  * Daiger, S. P. and Cavalli-Sforza, L. L. 1977. Detection of genetic variation with radioactive ligands. II. Genetic variants of vitamin D-labeled group-specific component (Gc)


proteins._Am. J. Hum. Genet._ 29: 593–604. CAS  PubMed  PubMed Central  Google Scholar  * Daiger, S. P., Schanfield, M. S., and Cavalli-Sforza, L. L. 1975. Human group-specific component


(Gc) proteins bind vitamin D and 25-hydroxy vitamin D._Prp. Natl. Acad. Sci._ 72: 2076–2080. Article  CAS  Google Scholar  * Hirschfeld, J. 1959. Immunoelectrophoretic demonstration of


qualitative differences in human sera and their relation to the haptoglobins._Acta Path. Microbiol. Scand._ 47: 160–168. Article  CAS  PubMed  Google Scholar  * Ishimoto, G., Kuwata, M., and


Nakajima, H. 1976. Further examples of Gc J variants found in paternity cases._Jap. J. Legal Med._ 30: 407–410 (in Japanese with English summary). Google Scholar  * Johnson, A. M., Cleve,


H., and Alper, C. 1975. Variants of the group-specific component system as demonstrated by immunofixation electrophoresis. Report of a new variant, Gc Boston (Gc B)._Am. J. Hum. Genet._ 27:


728–736. CAS  PubMed  PubMed Central  Google Scholar  * Laurell, C. B. 1965. Antigen-antibody crossed electrophoresis._Anal. Biochem._ 10: 358–361. Article  CAS  PubMed  Google Scholar  *


Nakajima, H., Ishimoto, G., and Kuwata, M. 1976. Further examples of Gc variant (Gc J) found in a Japanese family._Jap. J. Human Genet._ 21: 29–33. CAS  Google Scholar  * Omoto, K. 1975.


Distribution of polymorphic traits in the Japanese and neighbouring populations. 4. Serum protein groups. JIBP Synthesis, Vol. 2: 141–162. Google Scholar  * Omoto, K., Cleve, H., and Misawa,


S. 1972. A new variant phenotype of the group-specific component (Gc) found in a Japanese family._Jap. J. Human Genet._ 17: 1–9. Article  CAS  Google Scholar  Download references AUTHOR


INFORMATION AUTHORS AND AFFILIATIONS * Department of Legal Medicine, School of Medicine, Mie University, Tsu, Japan Mieko Kuwata & Goichi Ishimoto * Department of Forensic Medicine,


Tokyo Medical and Dental University, Tokyo, Japan Hachiro Nakajima Authors * Mieko Kuwata View author publications You can also search for this author inPubMed Google Scholar * Goichi


Ishimoto View author publications You can also search for this author inPubMed Google Scholar * Hachiro Nakajima View author publications You can also search for this author inPubMed Google


Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Kuwata, M., Ishimoto, G. & Nakajima, H. Group-specific component (Gc) polymorphism in


Japanese: An investigation on the phenotypic distribution with regard to the_Gc_ J allele. _Jap J Human Genet_ 23, 127–132 (1978). https://doi.org/10.1007/BF02001793 Download citation *


Received: 18 February 1978 * Published: 01 June 1978 * Issue Date: June 1978 * DOI: https://doi.org/10.1007/BF02001793 SHARE THIS ARTICLE Anyone you share the following link with will be


able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing


initiative KEYWORDS * Phenotypic Distribution * Common Phenotype * Codominant Allele * Immunofixation Electrophoresis * Fukushima Medical College


Trending News

Tv channel crew attacked by women in dadri; cameraperson injured

* Home * Viral * TV channel crew attacked by women in Dadri; cameraperson injured THE CREW OF NDTV WAS ALSO ATTACKED BY ...

Illinois pre-k teacher is found dead in car with state trooper husband in apparent murder-suicide

A pre-kindergarten teacher was fatally shot Monday by her Illinois State Trooper husband, who then turned the gun on him...

Obituaries - Oct. 21, 1996 - Los Angeles Times

Tom Girardi was a legal legend—until he was found guilty of stealing millions from his own clients. Host Madison McGhee ...

Gop tax cut plan survives challenges, heads for vote : congress: measure goes to house floor essentially intact after amendments are defeated. Child c

WASHINGTON — House Republicans on Tuesday fought off dozens of challenges to their plan to cut taxes by $189 billion ove...

And then there were 8: field narrows to replace johnson as nominations close

Nominations in the race to replace British Prime Minister Boris Johnson closed on Tuesday, with eight Conservative lawma...

Latests News

Group-specific component (gc) polymorphism in japanese: an investigation on the phenotypic distribution with regard to thegc j allele

SUMMARY Using the prolonged immunoelectrophoresis, Gc determination was performed in 1,347 plasma collected from 3 local...

Hollywood heart health—my generation

Memorial Day Sale! Join AARP for just $11 per year with a 5-year membership Join now and get a FREE gift. Expires 6/4  G...

Performance-based asset management system (pams): flood defence - phase 2

PERFORMANCE-BASED ASSET MANAGEMENT SYSTEM (PAMS): FLOOD DEFENCE - PHASE 2 A strategic risk and performance-based approac...

Why many gen-xers are closer to their parents than ever | members only

Memorial Day Sale! Join AARP for just $11 per year with a 5-year membership Join now and get a FREE gift. Expires 6/4  G...

Bruce springsteen rocks new york in front of bono, tony soprano and jon stewart

“New Yorkers: be afraid,” Bruce Springsteen scrawled atop his handwritten setlist for last night’s frenzied Madison Squa...

Top