Chronically lonely flies overeat and lose sleep

Nature

Chronically lonely flies overeat and lose sleep"


Play all audios:

Loading...

NEWS AND VIEWS 18 August 2021 Chronically lonely flies overeat and lose sleep The fruit fly Drosophila melanogaster is a social animal. Flies kept in chronic social isolation have now been


found to show dysregulated sleep and feeding patterns, casting light on how prolonged absence of social contact affects health. By Joel D. Levine0 Joel D. Levine Joel D. Levine is in the


Department of Biology, University of Toronto, Mississauga, Ontario L5L 1C6, Canada.


View author publications You can also search for this author in PubMed  Google Scholar


Twitter Facebook Email Access through your institution Buy or subscribe The neuroscientist Bruce McEwen wrote1 in 2002 that stress is the foremost public-health issue of our times, and that


“when activated chronically it can cause damage and accelerate disease”. Many stressors are of a social nature, and McEwen1 and others (see go.nature.com/3s3b4kw) noted with concern that


certain social pressures, such as poverty, inadequate education and violent crime, can contribute to the development of illnesses such as cancer, diabetes and depression. However, little is


understood about how these social pressures translate to disease. Writing in Nature, Li et al.2 present a fascinating and creative approach to modelling the effects of social context on an


individual’s health, using the fruit fly Drosophila melanogaster.

Access options Access through your institution Additional access options: Log in Learn about institutional subscriptions


Read our FAQs Contact customer support


Nature 597, 179-180 (2021)


doi: https://doi.org/10.1038/d41586-021-02194-2


References McEwen, B. & Lasley, E. N. The End of Stress As We Know It (Dana, 2002).


Google Scholar 


Li, W. et al. Nature 597, 239–244 (2021).


Article  Google Scholar 


Bourassa, C., McKay-McNabb, K. & Hampton, M. Can. Woman Stud. 24, 23–29 (2004).


Google Scholar 


Schneider, J., Atallah, J. & Levine, J. D. Adv. Genet. 77, 59–78 (2012).


Article  PubMed  Google Scholar 


Dawson, E. H. et al. Nature Commun. 9, 3574 (2018).


Article  PubMed  Google Scholar 


Sokolowski, M. B. Neuron 65, 780–794 (2010).


Article  PubMed  Google Scholar 


Tomova, L. et al. Nature Neurosci. 23, 1597–1605 (2020).


Article  PubMed  Google Scholar 


Hulse, B. K. et al. Preprint at bioRxiv https://doi.org/10.1101/2020.12.08.413955 (2020).


Donlea, J. M., Thimgan, M. S., Suzuki, Y., Gottschalk, L. & Shaw, P. J. Science 332, 1571–1576 (2011).


Article  PubMed  Google Scholar 


Lee, G., Bahn, J. H. & Park, J. H. Proc. Natl Acad. Sci. USA 103, 12580–12585 (2006).


Article  PubMed  Google Scholar 


Lee, C. R., Chen, A. & Tye, K. M. Cell 184, 1500–1516 (2021).


Article  PubMed  Google Scholar 


Ramdya, P. et al. Nature 519, 233–236 (2015).


Article  PubMed  Google Scholar 


Schneider, J., Dickinson, M. H. & Levine, J. D. Proc. Natl Acad. Sci. USA 109, 17174–17179 (2012).


Article  PubMed  Google Scholar 


Danchin, E. et al. Science 362, 1025–1030 (2018).


Article  PubMed  Google Scholar 


Bellen, H. J., Tong, C. & Tsuda, H. Nature Rev. Neurosci. 11, 514–522 (2010).


Article  PubMed  Google Scholar 


Download references


Reprints and permissions

Competing Interests


The author declares no competing interests.


Related Articles Read the paper: Chronic social isolation signals starvation and reduces sleep in Drosophila


How lactate links cannabis to social behaviour


Neural circuit evolved to process pheromone differently in two species of fruit fly


See all News & Views


Subjects Neuroscience Animal behaviour Latest on: Neuroscience False positives in study of memory-related gene expression


Matters Arising 04 JUN 25


Molecular gradients shape synaptic specificity of a visuomotor transformation


Article 04 JUN 25


Multi-timescale reinforcement learning in the brain


Article 04 JUN 25


Animal behaviour Clever cockatoos learn an easy way to quench their thirst


Research Highlight 03 JUN 25


Mother–infant bonds in wild chimpanzees resemble those of humans


News & Views 19 MAY 25


Can AI help us talk to dolphins? The race is now on


News 16 MAY 25


Jobs Professorship for Trauma, Hand and Reconstructive Surgery (W3) The Jena University Hospital (JUH) invites applications for a   Professorship for Trauma, Hand and Reconstructive Surgery


(W3)   to be filled at th...


Jena, Thüringen (DE)


Friedrich-Schiller-Universität Jena


Group Leader - Molecular Mechanisms of Environmental Adaptation EMBL is seeking a Group Leader to develop an independent research program on molecular mechanisms driving phenotype and


environmental response.


Rome (IT)


European Molecular Biology Laboratory (EMBL)


Faculty and Research Positions, Postdoctoral Recruitment Jointly sponsored by the Hangzhou Municipal People's Government and the University of Chinese Academy of Sciences.


Hangzhou, Zhejiang, China


Hangzhou Institute of Advanced Study, UCAS


Tenure-Track Assistant Professor at the Graduate School of Pharmaceutical Studies, Tohoku University The Graduate School of Pharmaceutical Studies at Tohoku Universities invites applications


for one open tenure-track assistant professor position.


Japan (JP)


Tohoku University


Postdocs in Genetic Epidemiology/Statistical Genetics The Di Angelantonio-Ieva group is seeking to recruit a highly motivated Postdoc in Genetic Epidemiology/Statistical Genetics in Human


Technopole.


Milan (IT)


Human Technopole


Trending News

Games to Take the Bite out of the Holiday

For me, it ranks somewhere between Arbor Day and Rutherford B. Hayes’ birthday. I never saw a werewolf I wanted to get t...

Nbpd wants a safe and fun fourth of july - newport beach news

The Newport Beach Police Department will have an enhanced presence around the city during  the holiday weekend. Starting...

Doxycycline plus methotrexate is more effective than methotrexate alone in early RA

O'Dell JR et al. (2006) Treatment of early seropositive rheumatoid arthritis: doxycycline plus methotrexate versus metho...

Expert witnesses | British Dental Journal

Download PDF Letter Published: 26 June 2020 Law and ethicsExpert witnesses J. Laszlo1 & M. McGowan1  British Dental Jour...

Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome

The coupled translocation of transfer RNA and messenger RNA through the ribosome entails large-scale structural rearrang...

Latests News

Chronically lonely flies overeat and lose sleep

NEWS AND VIEWS 18 August 2021 Chronically lonely flies overeat and lose sleep The fruit fly Drosophila melanogaster is a...

Purulia election result 2024 live updates: bjp's jyotirmay singh mahato has won this lok sabha seat

PURULIA LOK SABHA ELECTION RESULT 2024 LIVE UPDATES: With the counting of votes for the 2024 Lok Sabha elections underwa...

Double trouble | Nature Reviews Cancer

Access through your institution Buy or subscribe > Tumour growth was reduced only in _Pld1__−/−_ mice To investigate ...

Three ways to avoid being lonely this christmas

As the population ages and growing numbers of people are living alone, loneliness is emerging as a major public health i...

New retail at fashion island - newport beach news

Fashion Island is set to welcome four new retail tenants, including a first-in-California lifestyle and gift boutique an...

Top