Treatment, long-term outcome and prognostic variables in 214 unselected aml patients in sweden

ABSTRACT With the aim of describing an unselected series of acute myeloid leukaemias (AML) in adults, patients diagnosed 1987–1992 in the Örebro region of central Sweden were reviewed by

investigating hospital records. By utilizing: (1) The Swedish Cancer Registry, (2) The Cause of Death Registry, (3) listings of pathology bone marrow reports and (4) listings of inpatient

discharge diagnoses, we attempted to find all patients. Among secondary AML, only blast-crises of CML were excluded. A total of 214 cases of AML with a median age of 69.5 years were verified

corresponding to a mean yearly incidence in adults of 5.4/100 000. Of all patients, 56% had received ‘high-dose’ induction treatment, 28% ‘low-dose’ treatment and 16% no cytostatic

treatment. Median survival for all patients was 5.8 months and the probability of survival at 5 years was 9.3%. The 120 ‘high-dose’ treated patients had a total CR rate of 67%, median CR

duration 10.1 months and median survival 11.4 months. Age, LDH and kidney function were found to be independent prognostic variables for survival. The inclusion of patients unreferred from

district hospitals makes this study unique as an example of unselected AML. © 2000 Cancer Research Campaign SIMILAR CONTENT BEING VIEWED BY OTHERS FIRST REPORT FROM A SINGLE CENTER

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Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Division of Haematology, Department of Internal Medicine, Örebro Medical Center Hospital,

S-701 85, Örebro, Sweden M Åström & U Tidefelt * Unit of Biostatistics and Epidemiology, Örebro Medical Center Hospital, S-701 85, Örebro, Sweden L Bodin * Department of Internal

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permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Åström, M., Bodin, L., Nilsson, I. _et al._ Treatment, long-term outcome and prognostic variables in 214 unselected AML patients in Sweden.

_Br J Cancer_ 82, 1387–1392 (2000). https://doi.org/10.1054/bjoc.1999.1123 Download citation * Received: 16 June 1999 * Revised: 10 November 1999 * Accepted: 15 November 1999 * Published: 21

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shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * AML *

survival * selection * prognostic factors