Tolerance lies in the timing | Nature
Tolerance lies in the timing | Nature"
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During immune-cell development, potentially self-reactive T cells are eliminated. It emerges that recruitment of a co-receptor bound to the T-cell receptor by the enzyme Lck is the
rate-limiting step in this negative selection. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access
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subscriptions * Read our FAQs * Contact customer support REFERENCES * Stepanek, O. et al. _Cell_ 159, 333–345 (2014). Article CAS Google Scholar * McKeithan, T. W. _Proc. Natl Acad. Sci.
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Scholar Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Nicholas R. J. Gascoigne is in the Department of Microbiology, Yong Loo Lin School of Medicine, National University
of Singapore, 117597 Singapore., Nicholas R. J. Gascoigne Authors * Nicholas R. J. Gascoigne View author publications You can also search for this author inPubMed Google Scholar
CORRESPONDING AUTHOR Correspondence to Nicholas R. J. Gascoigne. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Gascoigne, N. Tolerance lies in the
timing. _Nature_ 515, 502–503 (2014). https://doi.org/10.1038/515502a Download citation * Published: 26 November 2014 * Issue Date: 27 November 2014 * DOI: https://doi.org/10.1038/515502a
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