The structure of the escherichia coli ef-tu· ef-ts complex at 2. 5 å resolution

ABSTRACT The crystal structure of the EF-Tu·EF-Ts complex from _Escherichia coli_ has been determined to a resolution of 2.5 Å. The complex contains two subunits of each of the elongation

factors. The two EF-Ts molecules form a tight dirtier, but there is little contact between the two EF-Tu molecules. The interaction of EF-Ts with EF-Tu results principally in the disruption

of the Mg2+ ion binding site, thereby reducing the affinity of EF-Tu for guanine nucleotides. Access through your institution Buy or subscribe This is a preview of subscription content,

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OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS CRYO-EM STRUCTURES OF _ESCHERICHIA COLI_ EC86

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AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * European Molecular Biology Laboratory, Grenoble Outstation, B.P. 156, 38042, Grenoble Cedex, France Takemasa Kawashima, Carmen

Berthet-Colominas, Stephen Cusack & Reuben Leberman * European Synchrotron Radiation Facility, B.P. 220, 38043, Grenoble Cedex, France Michael Wulff Authors * Takemasa Kawashima View

author publications You can also search for this author inPubMed Google Scholar * Carmen Berthet-Colominas View author publications You can also search for this author inPubMed Google

Scholar * Michael Wulff View author publications You can also search for this author inPubMed Google Scholar * Stephen Cusack View author publications You can also search for this author

inPubMed Google Scholar * Reuben Leberman View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS

ARTICLE CITE THIS ARTICLE Kawashima, T., Berthet-Colominas, C., Wulff, M. _et al._ The structure of the _Escherichia coli_ EF-Tu· EF-Ts complex at 2.5 Å resolution. _Nature_ 379, 511–518

(1996). https://doi.org/10.1038/379511a0 Download citation * Received: 25 October 1995 * Accepted: 19 December 1995 * Issue Date: 08 February 1996 * DOI: https://doi.org/10.1038/379511a0

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