Reversing the kinesin ratchet — a diverting tail
Reversing the kinesin ratchet — a diverting tail"
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The kinesins are a family of motor proteins that haul cellular cargo along microtubules in a stepwise fashion. Microtubules have an intrinsic polarity, with so-called ‘plus’ and ‘minus’
ends, and microtubule-binding motor proteins ‘read’ this polarity, and then move towards one end or the other. By laying down an organized array of microtubules and then attaching cellular
components to an appropriately directed motor, the cell can sort and segregate its components relative to the polarized array of microtubules: this kind of process is responsible for events
such as the spatial separation of two sets of chromosomes at cell division.
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