Abnormal or absent β mrna in β0 ferrara and gene deletion in δβ thalassaemia

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Abnormal or absent β mrna in β0 ferrara and gene deletion in δβ thalassaemia"


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ABSTRACT In patients with β0 thalassaemia from Ferrara, β globin mRNA sequences are either absent or structurally abnormal while in β0 thalassaemia in Catania, β globin mRNA sequences are


present. In δβ thalassaemia there is a deletion of β-like globin genes, while in β0 Catania DNA, no β globin gene deletion is detectable. Access through your institution Buy or subscribe


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NOVEL COMPOUND HETEROZYGOUS OF Β-THALASSEMIA WITH HBG-COUSHATTA: CASE REPORT OF IRAN Article Open access 15 May 2023 RARE COINHERITANCE OF HEMOGLOBIN VANCLEAVE WITH SEVERE BETA-THALASSEMIA


MUTATION IN A PATIENT WITH SECONDARY ERYTHROCYTOSIS Article Open access 23 April 2024 ABNORMAL HEMOGLOBIN ANTI-LEPORE HONG KONG COMPOUND WITH Β0-THALASSEMIA AMELIORATE THALASSEMIA SEVERITY


WHEN CO-INHERITED WITH Α-THALASSEMIA Article Open access 20 March 2024 REFERENCES * Weatherall, D. J., and Clegg, J. B., _The Thalassemia Syndromes_, 2nd ed. (Blackwell, Oxford, 1973).


Google Scholar  * Nienhuis, A. W., and Anderson, W. F., _J. clin. Invest._, 50, 2458–2460 (1971). Article  CAS  Google Scholar  * Benz, E. J., and Forget, B. G., _J. clin. Invest._ 50,


2755–2760 (1971). Article  CAS  Google Scholar  * Dow, L. W., _et al._, _Nature New Biol._, 243, 114–116 (1973). CAS  PubMed  Google Scholar  * Benz, E. J., Swerdlow, P. S., and Forget, B.


G., _Blood_, 45, 1–10 (1975). CAS  PubMed  Google Scholar  * Kacian, D. L., _et al._, _Proc. natn. Acad. Sci. U.S.A._, 70, 1886–1890 (1973). Article  ADS  CAS  Google Scholar  * Housman, D.,


Forget, B. G., Skoultchi, A., and Benz, E. J., Jr, _Proc. natn. Acad. Sci. U.S.A._ 70, 1809–1813 (1973), Article  ADS  CAS  Google Scholar  * Forget, B. G., Benz, E. J., Jr, Skoultchi, A.,


Baglioni, C., and Housman, D., _Nature_, 247, 379–381 (1974). Article  ADS  CAS  Google Scholar  * Ramirez, F., _et al._, _Proc. natn. Acad. Sci. U.S.A._, 72, 1550–1554 (1975). Article  ADS


  CAS  Google Scholar  * Ottolenghi, S., _et al._, _Proc. natn. Acad. Sci. U.S.A._, 72, 2294–2299 (1975). Article  ADS  CAS  Google Scholar  * Kan, Y. W., Holland, J. P., Dozy, A. M., and


Varmus, H. E., _Proc. natn. Acad. Sci. U.S.A._, 72, 5140–5144 (1975). Article  ADS  CAS  Google Scholar  * Tolstoshev, P., _et al._, _Nature_, 259, 95–98 (1976). Article  ADS  CAS  Google


Scholar  * Russo, G., Musumeci, S., Schilirò, G., D'Agata, A., and Pizzarelli, G., _Atti della. Società Italiana di Ematologia_, 1, 197–205 (1974). Google Scholar  * Bargellesi, A.,


Pontremoli, S., and Conconi, F., _Eur. J. Biochem._, 1, 71–73 (1937). Google Scholar  * Kan, Y. W., Holland, J. P., Dozy, A. M., Charache, S., and Kazazian, H. H., _Nature_, 258, 162–163


(1975). Article  ADS  CAS  Google Scholar  * Terada, M., _et al._, _Biochem. biophys. Res. Commun._, 47, 766–774 (1972). Article  CAS  Google Scholar  * Gambino, R., _et al._, _Proc. natn.


Acad. Sci. U.S.A._, 71, 3966–3970 (1974). Article  ADS  CAS  Google Scholar  * Conconi, F., _et al._, _Nature_, 254, 256–259 (1975). Article  ADS  CAS  Google Scholar  * Metafora, S.,


Terada, M., Dow, L. W., Marks, P. A., and Bank, A., _Proc. natn. Acad. Sci. U.S.A._, 69, 1299–1303 (1972). Article  ADS  CAS  Google Scholar  * Ramirez, F., _et al._, _J. biol. Chem._, 250,


6054–6058 (1975). CAS  PubMed  Google Scholar  * Lanyon, W. G., Ottolenghi, S., and Williamson, R., _Proc. natn. Acad. Sci. U.S.A._ 72, 258–262 (1975). Article  ADS  CAS  Google Scholar  *


Cann, A., Gambino, R., Banks, J., and Bank, A., _J. biol. Chem._, 249, 7536–7540 (1974). CAS  PubMed  Google Scholar  * Conconi, F., Rowley, P. T., del Senno, L., Pontremoli, S., and


Volpato, S., _Nature_, 238, 83–85 (1972). CAS  Google Scholar  * Forget, G. J., _et al._, _Cell_, 7, 323–329 (1976). Article  CAS  Google Scholar  * Huisman, T. H. J., _et al._, _Ann. N. Y.


Acad. Sci._, 232, 107–124 (1974). Article  ADS  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Columbia University, College of Physicians and


Surgeons, New York Francesco Ramirez, Joyce V. O'Donnell, Paul A. Marks & Arthur Bank * Pediatric Clinic, University of Catania, Italy Salvatore Musumeci, Gino Schilirò, Giuseppe


Pizzarelli & Giuseppe Russo * Laboratory of Molecular Embryology, Arco Felice, Naples, Italy Benedetta Luppis & Roberto Gambino Authors * Francesco Ramirez View author publications


You can also search for this author inPubMed Google Scholar * Joyce V. O'Donnell View author publications You can also search for this author inPubMed Google Scholar * Paul A. Marks


View author publications You can also search for this author inPubMed Google Scholar * Arthur Bank View author publications You can also search for this author inPubMed Google Scholar *


Salvatore Musumeci View author publications You can also search for this author inPubMed Google Scholar * Gino Schilirò View author publications You can also search for this author inPubMed 


Google Scholar * Giuseppe Pizzarelli View author publications You can also search for this author inPubMed Google Scholar * Giuseppe Russo View author publications You can also search for


this author inPubMed Google Scholar * Benedetta Luppis View author publications You can also search for this author inPubMed Google Scholar * Roberto Gambino View author publications You can


also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Ramirez, F., O'Donnell, J., Marks, P. _et al._


Abnormal or absent β mRNA in β0 Ferrara and gene deletion in δβ thalassaemia. _Nature_ 263, 471–475 (1976). https://doi.org/10.1038/263471a0 Download citation * Received: 13 April 1976 *


Accepted: 09 August 1976 * Issue Date: 07 October 1976 * DOI: https://doi.org/10.1038/263471a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content:


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