Assessment of cellular origin and ebv status in a ptld after double cord blood transplantation

Access through your institution Buy or subscribe Epstein–Barr virus-associated post-transplantation lymphoproliferative disorder (EBV-PTLD) has been well described as a complication

following allogeneic stem cell transplantation (SCT), but has only recently been reported after cord blood transplantation (CBT).1, 2 Some of the known risk factors for PTLD in bone marrow

transplantation are invariably present in CBT and can become contributing factors for PTLD: a relatively low dose of donor T cells, frequent donor–recipient human leukocyte antigen (HLA)

disparity and use of antithymocyte globulin (ATG) during conditioning. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution

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Contact customer support REFERENCES * Curtis RE, Travis LB, Rowlings PA, Socie G, Kingma DW, Banks PM _et al_. Risk of lymphoproliferative disorders after bone marrow transplantation: a

multi-institutional study. _Blood_ 1999; 94: 2208–2216. CAS  Google Scholar  * Gross TG, Steinbuch M, DeFor T, Shapiro RS, McGlave P, Ramsay NK _et al_. B cell lymphoproliferative disorders

following hematopoietic stem cell transplantation: risk factors, treatment and outcome. _BMT_ 1999; 23: 251–258. CAS  Google Scholar  * Sirvent N, Reviron D, de Lamballerie X, Michel G .

First report of Epstein–Barr virus lymphoproliferative disease after cord blood transplantation. _Bone Marrow Transplant_ 2000; 25: 120–121. Article  CAS  Google Scholar  * Ohga S, Kanaya Y,

Maki H, Takada H, Ohshima K, Kanda M _et al_. Epstein–Barr virus-associated lymphoproliferative disease after a cord blood transplant for Diamond–Blackfan anemia. _Bone Marrow Transplant_

2000; 25: 209–212. Article  CAS  Google Scholar  * Haut PR, Kovarik P, Shaw PH, Walterhouse D, Jenson HB, Kletzel M . Detection of EBV DNA in the cord blood for a patient developing

Epstein–Barr virus-associated lymphoproliferative disorder following mismatched unrelated umbilical cord blood transplantation. _Bone Marrow Transplant_ 2001; 27: 761–765. Article  CAS 

Google Scholar  * Barker JN, Martin PL, Coad JE, DeFor T, Trigg ME, Kurtzberg J _et al_. Low incidence of Epstein–Barr virus-associated posttransplantation lymphoproliferative disorders in

272 unrelated-donor umbilical cord blood transplant recipients. _Biol Blood Marrow Transplant_ 2001; 7: 395–399. Article  CAS  Google Scholar  * Shimasaki N, Mori T, Shimada H, Sugita M,

Higuchi M, Mukai M _et al_. Epstein–Barr virus-associated posttransplant lymphoproliferative disorder after a cord blood stem cell transplantation presenting with pulmonary nodules. _J

Pediatr Hematol Oncol_ 2004; 26: 124–127. Article  Google Scholar  * Brunstein C, Weisdorf DJ, DeFor T, Barker JN, Tolar J, van Burik JA _et al_. Marked increased risk of Epstein–Barr

virus-related complications with the addition of antithymocyte globulin to a nonmyeloablative conditioning prior to unrelated umbilical cord blood transplantation. _Blood_ 2006; 108:

2874–2880. Article  CAS  Google Scholar  * van Esser JW, Niesters HG, van der Holt B, Meijer E, Osterhaus AD, Gratama JW _et al_. Prevention of Epstein–Barr virus-lymphoproliferative disease

by molecular monitoring and preemptive rituximab in high-risk patients after allogeneic stem cell transplantation. _Blood_ 2002; 99: 4364–4369. Article  CAS  Google Scholar  * Gong JZ,

Bayerl MG, Sandhaus LM, Sebastian S, Rehder CW, Routbort M _et al_. Posttransplant lymphoproliferative disorder after umbilical cord blood transplantation in children. _Am J Surg Pathol_

2006; 30: 328–336. Article  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Istituto di Ematologia, Università Cattolica, Rome, Italy G Reddiconto, P

Chiusolo, A Fiorini, G Farina, L Laurenti, G Leone & S Sica * Istituto di Anatomia Patologica, Università Cattolica, Rome, Italy M Martini * Istituto di Microbiologia, Università

Cattolica, Rome, Italy S Marchetti & G Fadda Authors * G Reddiconto View author publications You can also search for this author inPubMed Google Scholar * P Chiusolo View author

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View author publications You can also search for this author inPubMed Google Scholar * S Marchetti View author publications You can also search for this author inPubMed Google Scholar * G

Fadda View author publications You can also search for this author inPubMed Google Scholar * G Leone View author publications You can also search for this author inPubMed Google Scholar * S

Sica View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to G Reddiconto. RIGHTS AND PERMISSIONS Reprints and permissions

ABOUT THIS ARTICLE CITE THIS ARTICLE Reddiconto, G., Chiusolo, P., Fiorini, A. _et al._ Assessment of cellular origin and EBV status in a PTLD after double cord blood transplantation.

_Leukemia_ 21, 2552–2554 (2007). https://doi.org/10.1038/sj.leu.2404818 Download citation * Published: 28 June 2007 * Issue Date: December 2007 * DOI: https://doi.org/10.1038/sj.leu.2404818

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