Absorption of d-glucose by the rabbit jejunum during cholera toxin-induced diarrhoea

ABSTRACT CHOLERA exotoxin causes fluid production by the intestine when instilled into jejunal or ileal loops of anaesthetized rabbits1–3. Profuse quantities of isotonic fluid are produced

by the small intestine without histological alteration of the mucosa4. The pathogenesis of the increased fluid production by the intestine in cholera is unsettled. It has not been determined

whether the fluid production is the result of increased intestinal secretion, decreased intestinal absorption or a combination of these two factors. To assess the importance of altered

intestinal absorption, absorption of _d_-glucose by the rabbit jejunum was measured both in the presence and absence of cholera diarrhoea. Access through your institution Buy or subscribe

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references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Johns Hopkins University School of Medicine, Baltimore, Maryland HAROLD A. SEREBRO, THEODORE M. BAYLESS, THOMAS R. HENDRIX, FRANK L.

IBER & THOMAS MCGONAGLE Authors * HAROLD A. SEREBRO View author publications You can also search for this author inPubMed Google Scholar * THEODORE M. BAYLESS View author publications

You can also search for this author inPubMed Google Scholar * THOMAS R. HENDRIX View author publications You can also search for this author inPubMed Google Scholar * FRANK L. IBER View

author publications You can also search for this author inPubMed Google Scholar * THOMAS MCGONAGLE View author publications You can also search for this author inPubMed Google Scholar RIGHTS

AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE SEREBRO, H., BAYLESS, T., HENDRIX, T. _et al._ Absorption of _d_-Glucose by the Rabbit Jejunum during Cholera

Toxin-induced Diarrhoea. _Nature_ 217, 1272–1273 (1968). https://doi.org/10.1038/2171272a0 Download citation * Received: 29 January 1968 * Issue Date: 30 March 1968 * DOI:

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