Mitochondrial pyridine nucleotides in the oxidation of isocitrate and malate

ABSTRACT CHAPPEL1,2 has shown that the rate of uptake of oxygen by rat liver mitochondria, with isocitrate in the presence of malate, is greater than the sum of that observed when either

substrate is present alone. Since the oxidation of both isocitrate and malate is linked to pyridine nucleotides, the composition of pyridine nucleotides during the oxidation of these

substrates was measured. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your

institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access

to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our

FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS THERMODYNAMIC EFFICIENCY, REVERSIBILITY, AND DEGREE OF COUPLING IN ENERGY CONSERVATION BY THE MITOCHONDRIAL

RESPIRATORY CHAIN Article Open access 18 August 2020 ASSOCIATION OF THE MALATE DEHYDROGENASE-CITRATE SYNTHASE METABOLON IS MODULATED BY INTERMEDIATES OF THE KREBS TRICARBOXYLIC ACID CYCLE

Article Open access 21 September 2021 TRACING THE LACTATE SHUTTLE TO THE MITOCHONDRIAL RETICULUM Article Open access 08 September 2022 REFERENCES * Chappel, J. B., in _Biol. Structure and

Fctn._, edit. by Goodwin, T. W., and Lindberg, O., 2, 71 (Academic Press, New York, 1961). Google Scholar  * Chappel, J. B., _Biochem. J._, 90, 225 (1964). Article  Google Scholar  *

Estabrook, R. W., _Anal. Biochem._, 4, 231 (1964). Article  Google Scholar  * Hogeboom, G. H., in _Methods of Enzymology_, edit. by Colowick, S. P., and Kaplan, N. O., 1, 16 (Academic Press,

New York, 1961). Google Scholar  * Chance, B., and Baltscheffsky, H., _J. Biol. Chem._, 233, 736 (1958). CAS  PubMed  Google Scholar  * Henley, K. S., Napier, jun., E. A., Kreyden, R. W.,

Corssen, G. C., and Berendsohn, S., _J. Lab. Clin. Med._, 64, 306 (1964). CAS  PubMed  Google Scholar  * Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., _J. Biol. Chem._,

193, 265 (1951). CAS  PubMed  Google Scholar  * Chance, B., in _CIBA Symp. Regulation of Cell Metabolism_, edit. by Wolstenholme, G. E. W., and O'Connor, C. M., 91 (Little, Brown and

Co., Boston, 1959). Google Scholar  * Klingenberg, M., in _Energy-linked Functions of Mitochondria_, edit. by Chance, B., 121 (Academic Press, New York, 1963). Book  Google Scholar  Download

references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Internal Medicine, Section of Gastroenterology, University of Michigan Medical School, Ann Arbor, Michigan KEITH S.

HENLEY & EARL G. LAUGHREY Authors * KEITH S. HENLEY View author publications You can also search for this author inPubMed Google Scholar * EARL G. LAUGHREY View author publications You

can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE HENLEY, K., LAUGHREY, E. Mitochondrial Pyridine

Nucleotides in the Oxidation of Isocitrate and Malate. _Nature_ 205, 707–708 (1965). https://doi.org/10.1038/205707a0 Download citation * Published: 01 February 1965 * Issue Date: 13

February 1965 * DOI: https://doi.org/10.1038/205707a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable

link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative