Behaviour of zinc and radiozinc in tumour-bearing rats

ABSTRACT THE distribution of zinc-65 in the tissues of rats, following intravenous injection of a ‘65Zn-serurn-protein complex’, has been studied by Gilbert and Taylor1 who showed that the

zinc-65 rapidly became uniformly distributed throughout the zinc contained in the soft tissues. These authors concluded that the zinc in the soft tissues could be considered to exist in one

large ‘soft tissue zinc pool’ freely exchanging with the zinc in the plasma. As a result of preliminary measurements in rats bearing subcutaneously implanted tumours it was suggested that

the tumour could probably be considered to form part of the soft tissue pool. In this report the distribution of zinc-65 in the tissues of rats bearing a subcutaneous mammary tumour is

described and it is shown that the zinc in the tumour can be considered to form part of the soft tissue zinc pool. Access through your institution Buy or subscribe This is a preview of

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INFLUENCE ON THE ELEMENTAL HOMEOSTASIS OF THE DISTANT ORGANS: THE RESULTS OF INTER-COMPARISON STUDY CARRIED OUT WITH TXRF METHOD Article Open access 13 January 2024 ESTIMATION OF RADIATION

DOSE FROM INGESTED TRITIUM IN HUMANS BY ADMINISTRATION OF DEUTERIUM-LABELLED COMPOUNDS AND FOOD Article Open access 02 February 2021 DECREASING UNDESIRABLE ABSORBED RADIATION TO THE

INTESTINE AFTER ADMINISTRATION OF RADIUM-223 DICHLORIDE FOR TREATMENT OF BONE METASTASES Article Open access 17 July 2020 REFERENCES * Gilbert, I. G. F., and Taylor, D. M., _Biochem.

Biophys. Acta_, 21, 551 (1956). Article  Google Scholar  * Bartholomew, M. E., Tupper, R., and Wormall, A., _Biochem. J._, 71, 15, P (1959). Google Scholar  Download references AUTHOR

INFORMATION AUTHORS AND AFFILIATIONS * Department of Physics, Institute of Cancer Research, Royal Cancer Hospital, London, S.W.3 D. M. TAYLOR Authors * D. M. TAYLOR View author publications

You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE TAYLOR, D. Behaviour of Zinc and Radiozinc in

Tumour-Bearing Rats. _Nature_ 184, 1649–1650 (1959). https://doi.org/10.1038/1841649a0 Download citation * Issue Date: 21 November 1959 * DOI: https://doi.org/10.1038/1841649a0 SHARE THIS

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